Clinical Trials in Philadelphia

Showing 5961-5980 of 20,904 trials

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

NCT04113434

The overall goal of the study is to risk stratify pediatric Acute Respiratory Distress Syndrome (ARDS) patients and to identify sub-phenotypes with shared biology in order to appropriately target therapies in future trials. This is a prospective, multicenter study of 500 intubated children with ARDS, with planned blood collection within 24 hours of ARDS onset and subsequent measurement of plasma protein biomarkers and peripheral blood gene expression.

Acute Respiratory Distress Syndrome

Children's Hospital of Philadelphia500 participantsStarted Jan 2020

Little Rock, Arkansas, United States • Aurora, Colorado, United States • Miami, Florida, United States +13 more locations

Active Not RecruitingPhase 4< 1 mile

Risk Assessment of Carotid Plaques Using 3D Contrast-Enhanced Ultrasound

NCT04643431

This is an open-label, non-randomized study conducted at Thomas Jefferson University comparing pressure-gradient estimates (obtained between a carotid plaque and the carotid artery) to imaging and histology markers of plaque vulnerability. There is an inverse relationship between the subharmonic signal magnitude from contrast-enhanced ultrasound microbubbles and ambient pressure. This pressure estimation technique (referred as SHAPE) will be used to estimate the pressure gradient across the carotid plaque cap noninvasively in vivo.

Carotid Atherosclerosis

Thomas Jefferson University20 participantsStarted Dec 2020

Philadelphia, Pennsylvania, United States

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

Risk Assessment of Carotid Plaques Using 3D Contrast-Enhanced Ultrasound

Find Trials by Condition in Philadelphia

A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness

Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Improving Participation in Universal School Meals (USM)

PEACE for ImPACT Study

LaPPS: Labor Podcast for Patient Satisfaction

Improving Patient Experience: BMBA

HiLo: Pragmatic Trial of Higher vs Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis

Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma

Non-invasive Brain Stimulation in Children With Autism

Genes and Environment in Multiple Sclerosis

Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System

MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS)

DALY II USA/ MB-CART2019.1 for DLBCL

Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency

Prophylaxis and Treatment of COVID-19

Predictive Analytics and Clinical Decision Support to Improve PrEP Prescribing

A Study of BI-1206 in Combination With Rituximab With or Without Acalabrutinib in Subjects With Indolent B-Cell NHL

Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA