Clinical Trials in Philadelphia

Showing 461-480 of 9,968 trials

Pulmonary Assessment in Thoracic Insufficiency Syndrome Patients

NCT04977830

Thoracic insufficiency syndrome (TIS) is a complex condition that involves chest wall deformities that can affect normal breathing and lung growth. In most cases, children with TIS are also born with spine disorders such as scoliosis. The inability of the thorax to support normal respiration or lung growth can cause respiratory distress and even mortality. Investigators aim to validate MRI imaging sequences to use as an assessment tool for pulmonary function.

Thoracic Insufficiency Syndrome

Patrick Cahill, MDStarted Jan 2026

Philadelphia, Pennsylvania, United States

COMPLETEDPHASE3< 1 mile

Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)

NCT06354660

The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes and inadequate glycemic control. The study will last about 11 months and may include up to 11 visits.

Diabetes Type 2

Eli Lilly and Company537 participantsStarted Apr 2024

Scottsdale, Arizona, United States • Tucson, Arizona, United States • Canoga Park, California, United States +45 more locations

Pulmonary Assessment in Thoracic Insufficiency Syndrome Patients

Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)

Find Trials by Condition in Philadelphia

DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery

The Radiation Oncology Registry and Biosample Repository

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

A Study of Mogamulizumab to Prevent Adult T-cell Leukemia/Lymphoma in People With HTLV-1

Impella ECP Study (ECP Study) and Impella ECP Continued Access Protocol

A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Trifecta-Lung cfDNA-MMDx Study

Phase II Trial of Lung Chemoemobolization

Personalized Reduction of Chemotherapy Intensity Through ctDNA Evaluation for the Treatment of Patients With Advanced Hodgkin Lymphoma

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A

Lumason® Infusion vs. Bolus Administrations

A Study to Evaluate the Effect of Budesonide, Glycopyrronium, Formoterol Fumarate (BGF) Metered Dose Inhaler (MDI), Budesonide and Formoterol Fumarate (BFF) MDI and Placebo MDI on Exercise Parameters in Participants With Chronic Obstructive Pulmonary Disease (COPD).

Long-term Safety and Efficacy Study of Riliprubart in Participants With CIDP