Clinical Trials in Philadelphia

Showing 4621-4640 of 15,860 trials

MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

NCT03585764

Phase I study to establish safety and feasibility of intraperitoneally administered lentiviral transduced MOv19-BBz CAR T cells with or without cyclophosphamide + fludarabine as lymphodepleting chemotherapy

Ovarian CancerFallopian Tube CancerPrimary Peritoneal Carcinoma

University of Pennsylvania46 participantsStarted Oct 2018

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

A Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799)

NCT03631784

This is a trial in adult participants with unresectable, locally advanced, Stage III non-small cell lung cancer (NSCLC) treated with pembrolizumab in combination with platinum doublet chemotherapy and standard thoracic radiotherapy followed by pembrolizumab monotherapy. The primary hypothesis of the trial is that within each platinum doublet chemotherapy cohort, the percentage of participants who develop Grade 3 or higher pneumonitis is ≤10% and estimation of objective response rate (ORR) by blinded independent central review (BICR).

Non-small Cell Lung Cancer

Merck Sharp & Dohme LLC216 participantsStarted Oct 2018

Santa Rosa, California, United States • Evanston, Illinois, United States • Fort Wayne, Indiana, United States +53 more locations

MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

A Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799)

Find Trials by Condition in Philadelphia

PArtial REbreathing for Migraine With Aura 1

Effects of Ketone Supplementation on Acute Alcohol Withdrawal

Safety and Efficacy of the SurVeil™ Drug-Coated Balloon

A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis

SUBLOCADE Rapid Initiation Extension Study

SUBLOCADE Rapid Initiation Study

Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)

A Study of LY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events

A Prospective Observational Study of TPIAT

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging

Walking and mHealth to Increase Participation in Parkinson Disease

Urine CXCL10 Monitoring Trial in Kidney Transplant

A Phase 1, Open Label Study of Intravenous GSK3745417 to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Determine RP2D & Schedule in Participants With Relapsed or Refractory Myeloid Malignancies Including AML and HR MDS

Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis

Study to Investigate Hepatic Impairment on PK, Safety, Tolerability of Camizestrant in Post-Menopausal Female Subjects