Clinical Trials in Philadelphia

Showing 4521-4540 of 15,860 trials

COMPLETED< 1 mile

R3 Delta Ceramic Acetabular System PAS U.S.

NCT03056534

R3 Delta Post-Approval Study U.S.

Degenerative Joint Disease

Smith & Nephew, Inc.189 participantsStarted Feb 2018

Tampa, Florida, United States • Tucker, Georgia, United States • Annapolis, Maryland, United States +5 more locations

Enrolling By InvitationPhase 3< 1 mile

A Phase 3 Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

NCT06431893

The goal of this long-term extension (LTE) study is to evaluate the safety and efficacy of pegtibatinase in patients with classical homocystinuria (HCU). Patients who are active in the Phase 1/2 COMPOSE study or those who complete the 24 weeks of treatment in the Phase 3 HARMONY are eligible to participate. Participants will be in this clinical study for up to about 13 months including: * a treatment period of up to 104 weeks * a 4-week safety follow-up period

Homocystinuria

Travere Therapeutics, Inc.100 participantsStarted Apr 2024

Portland, Maine, United States • New York, New York, United States • Morrisville, North Carolina, United States +1 more locations

R3 Delta Ceramic Acetabular System PAS U.S.

A Phase 3 Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

Find Trials by Condition in Philadelphia

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53

A Randomized, Controlled Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical Reperfusion System (SUMMIT MAX)

Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy

AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke

Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

Electrical Stimulation Effect on Ankle Instability During Walking in Virtual Reality Setup

Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

FlowMet-R Blood Flow Measurement for the Diagnosis of Peripheral Artery Disease and Critical Limb Ischemia

Calypso Knee System Clinical Study

Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD

A Study to Characterize Adverse Events Occurring Within One Day of TEGSEDI Administration to Adult Participants With hATTR-PN

A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequately Controlled by H1 Antihistamines

Amivantamab in Adenoid Cystic Carcinoma

Study to Evaluate the Efficacy of a Probiotic in Infantile Colic Symptoms Relief

A Bioequivalence Study of Bimekizumab Given as 1x2mL or 2x1mL Subcutaneous Injection Using an Autoinjector in Healthy Study Participants