Clinical Trials in Philadelphia

Showing 4281-4300 of 15,860 trials

Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery

NCT03184038

This phase II trial studies the neurological function in patients with multiple brain metastases undergoing stereotactic radiosurgery (SRS) or stereotactic body radiation therapy (SBRT). Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method can kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. Assessment of neurocognitive function may help show that SRS preserves neurological function in patients with multiple brain metastases better than SBRT.

Metastatic Malignant Neoplasm in the BrainMetastatic Malignant Solid Neoplasm

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University90 participantsStarted Feb 2017

Sewell, New Jersey, United States • Philadelphia, Pennsylvania, United States

RECRUITINGPhase 1/2< 1 mile

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

NCT04104776

The purpose of this open-label, first-in-human (FIH) trial is to evaluate the safety, tolerability, and preliminary clinical activity of Tulmimetostat as a monotherapy in patients with advanced solid tumors and lymphomas.

Advanced Solid TumorDiffuse Large B Cell LymphomaLymphoma, T-Cell+5 more

Novartis Pharmaceuticals275 participantsStarted Sep 2019

Atlanta, Georgia, United States • Chicago, Illinois, United States • Baltimore, Maryland, United States +57 more locations

Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

Find Trials by Condition in Philadelphia

Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions

Real-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers, RT-CAMSS Study

STAT Inhibitor OPB-111077, Decitabine and Venetoclax in Treating Patients With Acute Myeloid Leukemia That Is Refractory, Relapsed or Newly Diagnosed and Ineligible for Intensive Chemotherapy

Tornier Shoulder Outcomes Study to Examine Safety and Functional Outcomes in Shoulder Arthroplasty and Fracture Patients

A Study to Assess the Effects of Dexpramipexole in Participants With Eosinophilic COPD

A Biomarker-Guided, Randomized, Placebo-Controlled Efficacy and Safety Study of Liafensine in Patients With TRD

Osteogenesis Imperfecta Blood Pressure Study

Effectiveness and Safety Study of Etomidate Versus Midazolam to Help Place a Breathing Tube Outside of the Hospital.

A Study of ES002023 (Anti-CD39 Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors

7-week Study With CT-155 in People With Schizophrenia

A Study of IMR-687 in Subjects With Sickle Cell Disease

Dose-Ranging Study of ST-920, an AAV2/6 Human Alpha Galactosidase A Gene Therapy in Subjects With Fabry Disease (STAAR)

REC 0/0559 Eye Drops for Treatment of Moderate and Severe Neurotrophic Keratitis in Adult Patients

Extension Study to Evaluate the Long-Term Outcomes of Pediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe-ROP-1920 Study (Acronym: Butterfleye Next)

A Trial Evaluating the Safety and Effects of an RNA Vaccine ARCT-021 in Healthy Adults

Mohala Na Pua: Community-driven Drug Prevention

A Study to Assess Adverse Events and Change in Disease Activity of HArmonyCa Lidocaine Injectable Gel for Mid Face Soft Tissue Augmentation in Adult Participants

Multiple Ascending Dose Safety, Tolerability, PK Study of AL001 in Alzheimer's Disease Patients & Healthy Adult Subjects