Clinical Trials in Philadelphia

Showing 3321-3340 of 20,904 trials

Rehab CARES In USA: Clinical Trial

NCT05542121

In Phase 2, Patients in a community-based setting who have had a stroke will be evaluated by rehabilitation professionals and asked to perform a battery of clinical assessments before and after standard of care and robot assisted therapy with Rehab CARES system of simple force-feedback robots that are adapted to deliver single and group therapy.

StrokeHemiplegia

University of Pennsylvania27 participantsStarted Jun 2022

Philadelphia, Pennsylvania, United States • Philadelphia, Pennsylvania, United States

COMPLETED< 1 mile

Biodesign® Otologic Repair Graft

NCT04635228

The post-market follow-up clinical trial of the Cook® Biodesign® Otologic Repair Graft will follow patients up to 3 months post-implantation to determine the percent of patients with complete closure of the tympanic membrane.

Tympanic Membrane PerforationEardrum Perforation

Cook Research Incorporated87 participantsStarted Sep 2021

Indianapolis, Indiana, United States • Cincinnati, Ohio, United States • Cleveland, Ohio, United States +2 more locations

COMPLETEDPhase 3< 1 mile

Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)

NCT04458051

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary Objectives: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety and tolerability of SAR442168 To evaluate population pharmacokinetics (PK) of SAR442168 in PPMS and its relationship to efficacy and safety To evaluate pharmacodynamics of SAR442168

Primary Progressive Multiple Sclerosis

Sanofi767 participantsStarted Aug 2020

La Jolla, California, United States • Los Alamitos, California, United States • Los Angeles, California, United States +274 more locations

Rehab CARES In USA: Clinical Trial

Biodesign® Otologic Repair Graft

Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)

Find Trials by Condition in Philadelphia

Resting State Changes Following Theta Burst Stimulation

Treating Young Children With Attention Deficit Hyperactivity Disorder

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

RT With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer

Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors

A Study of Multiparametric Ultrasound Imaging (mpUS) for People With Endometrial Cancer

Study Evaluating the Safety, Efficacy and Tolerability of BIO89-100 in Subjects With Biopsy-confirmed Nonalcoholic Steatohepatitis (NASH)

A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy

Acupuncture for Chronic Low Back Pain in Older Adults

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia

A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

[18F]PI-2620 Phase 3 Histopathological Study

Study of Ibrutinib in Combination With Revlimid/Dexamethasone in Relapsed/Refractory Multiple Myeloma

Mechanisms of Exposure Therapy for OCD

Low INR to Minimize Bleeding With Mechanical Valves Trial

DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer

Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.