Clinical Trials in Pennsylvania

Showing 19161-19180 of 19,675 trials

Sirolimus and Cyclosporine for Treatment-Resistant Aplastic Anemia

NCT00319878

Aplastic anemia is a rare autoimmune disorder in which the bone marrow production of blood cells is greatly decreased or absent. Symptoms include fatigue, weakness, tiny reddish-purple marks on the skin, abnormal bruising, and bleeding from the gums, nose, or intestine. While some cases of aplastic anemia are caused by medications, toxic exposures, or inherited genes, most often the cause remains unknown. The purpose of this study is to determine the safety and efficacy of combining two drugs, sirolimus and cyclosporine, for treating individuals with aplastic anemia that has not responded to other treatments.

Anemia, Aplastic

Office of Rare Diseases (ORD)52 participantsStarted May 2006

Los Angeles, California, United States • Tampa, Florida, United States • Cleveland, Ohio, United States +1 more locations

COMPLETEDPhase 261 miles

Evaluate the Effects of GPI 1485 on Erectile Function Following Bilateral Nerve-Sparing Prostatectomy

NCT00090376

In this phase II study, an investigative (not approved by the FDA) drug called GPI 1485 is being assessed to see if it can help preserve erectile function after prostatectomy.

ImpotenceProstate Cancer

Eisai Inc.240 participantsStarted Dec 2003

Phoenix, Arizona, United States • La Mesa, California, United States • Stanford, California, United States +22 more locations

Sirolimus and Cyclosporine for Treatment-Resistant Aplastic Anemia

Evaluate the Effects of GPI 1485 on Erectile Function Following Bilateral Nerve-Sparing Prostatectomy

Find Trials by Condition in Pennsylvania

Efficacy of XP20B Following Bunionectomy Surgery

Proof of Concept Study of Cognitive Improvement in Patients With Schizophrenia

STA-4783 in Combination With Paclitaxel and Carboplatin for the Treatment of Chemotherapy Naive Patients With Stage IIIB/IV Non Small Cell Lung Cancer (NSCLC)

Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Due to Spinal Cord Injury

Demonstrate Exubera Works As Well As Avandia When Added To Sulfonylurea + Metformin In Controlling Glucose

Study Of SU011248 In Patients With Metastatic Non-Small Cell Lung Cancer

A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)

Attain StarFix™ Model 4195 Left Ventricular Lead

A Study of ATN-224 and Bortezomib in Patients With Multiple Myeloma

Efficacy Study of Tempol to Prevent Hair Loss From Radiotherapy to the Brain

A Safety and Efficacy Study for Treatment of Painful Vertebral Compression Fractures Caused by Osteoporosis

A Research Study to Compare the Treatments of a Combination of Elzasonan With Zoloft, to Zoloft Alone, or Placebo in People With Major Depressive Disorder (MDD)

Dose-Escalation Study of CG0070 for Bladder Cancer After BCG (Bacillus Calmette-Guerin) Failure

Vein-Coronary Atherosclerosis And Rosiglitazone After Bypass Surgery: The VICTORY Trial

MAD in Cancer Patients: Safety of BMS-582664 in Patients With Advanced or Metastatic Solid Tumors

An Observational Study of Burden of Upper GI-Symptoms in CV Risk Patients

A Phase 2b Study of DIO-902 or DIO-902 Placebo in Addition to Metformin and Atorvastatin or Atorvastatin Placebo for Type 2 Diabetes

Study to Demonstrate the Clinical Efficacy of Levofloxacin in the Treatment of Pneumonia