Clinical Trials in Pennsylvania

Showing 421-440 of 9,383 trials

A Study to Investigate the Pharmacokinetics and Safety of Risdiplam in Infants With Spinal Muscular Atrophy

NCT05808764

This study will evaluate the pharmacokinetics (PK) and safety of risdiplam in participants with spinal muscular atrophy (SMA) under 20 days of age at first dose.

Muscular Atrophy, Spinal

Hoffmann-La Roche10 participantsStarted Apr 2024

Chicago, Illinois, United States • Ann Arbor, Michigan, United States • Gordonville, Pennsylvania, United States +10 more locations

RECRUITINGPHASE290 miles

Pembrolizumab, Olaparib, and Temozolomide for People With Glioma

NCT05188508

This study will test the safety and effectiveness of a combination of pembrolizumab, olaparib, and temozolomide to see how well these drugs work when given together in people with a glioma that either did not respond to previous treatment or came back after treatment.

Glioma

Memorial Sloan Kettering Cancer Center57 participantsStarted Jan 2022

Hartford, Connecticut, United States • Miami, Florida, United States • Basking Ridge, New Jersey, United States +7 more locations

A Study to Investigate the Pharmacokinetics and Safety of Risdiplam in Infants With Spinal Muscular Atrophy

Pembrolizumab, Olaparib, and Temozolomide for People With Glioma

Find Trials by Condition in Pennsylvania

Optimize Low Back Pain

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP

Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: The STEMI-DTU Trial

Clinical and Genetic Studies of X-Linked Juvenile Retinoschisis

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

Lu AF28996 in Participants With Parkinson's Disease (PD)

Direct Access Carotid Artery Stenting Using the Neuroguard IEP System (PERFORMANCE III)

A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumors

MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach

A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant

A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts

A Study of Doxycycline to Treat Chlamydial Infection

Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors (MK-1200-002)

A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA