Clinical Trials in Pennsylvania

Showing 2541-2560 of 9,383 trials

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

NCT04113434

The overall goal of the study is to risk stratify pediatric Acute Respiratory Distress Syndrome (ARDS) patients and to identify sub-phenotypes with shared biology in order to appropriately target therapies in future trials. This is a prospective, multicenter study of 500 intubated children with ARDS, with planned blood collection within 24 hours of ARDS onset and subsequent measurement of plasma protein biomarkers and peripheral blood gene expression.

Acute Respiratory Distress Syndrome

Children's Hospital of Philadelphia500 participantsStarted Jan 2020

Little Rock, Arkansas, United States • Aurora, Colorado, United States • Miami, Florida, United States +13 more locations

COMPLETEDPhase 336 miles

Long-term Follow-up Study With Darvadstrocel in the Treatment of Complex Perianal Fistula

NCT04075825

The main aim is to follow-up on long term side effect and symptom improvement of Darvadstrocel in the treatment of complex perianal fistula in adults. Participants will not receive any drug in this study.

Crohn's DiseaseComplex Perianal Fistula

Takeda150 participantsStarted Nov 2019

San Francisco, California, United States • West Hollywood, California, United States • New Haven, Connecticut, United States +55 more locations

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

Long-term Follow-up Study With Darvadstrocel in the Treatment of Complex Perianal Fistula

Find Trials by Condition in Pennsylvania

Utility of the Superior Vena Cava Collapsibility Index (SVC-CI) to Predict Fluid Responsiveness in Patients With Coronary Artery Disease Undergoing Surgical Revascularization

A Study of Apalutamide (Adjuvant Treatment) and Androgen Deprivation Therapy (ADT) in Participants Who Have Undergone Radical Prostatectomy (RP) for Non-metastatic Prostate Cancer and Who Are at High Risk for Metastases

A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression

Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma

DALY II USA/ MB-CART2019.1 for DLBCL

Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors

HiLo: Pragmatic Trial of Higher vs Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis

Burn Validation Study

Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)

A Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness

Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency

Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer

AI Derived Biomarker to Select Neoadjuvant Treatment for Borderline Resectable Pancreatic Ductal Adenocarcinoma

Study to Determine if Contacting Patients With MTC More Frequently Results in Earlier Detection and Treatment of Signs and Symptoms of AEs and Thus a Decrease in the Percentage of Time Patients Experience AEs During First 12 Months on Vandetanib Treatment

Assessment of a Non-invasive Device in the Management of Open Abdomen (AbCLO)

A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus

Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA