Clinical Trials in Pennsylvania

Showing 2361-2380 of 9,383 trials

Maintenance Obinutuzumab in Treating Patients With Central Nervous System Lymphoma Who Have Achieved a Complete or Partial Response

NCT06175000

This randomized phase II trial studies how well obinutuzumab works as maintenance treatment in patients with central nervous system lymphoma who have achieved the disappearance of all signs of cancer in response to treatment (complete response) or a decrease in the size of a tumor, or in the extent of cancer in the body, in response to treatment (partial response). Immunotherapy with obinutuzumab, may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread.

Primary Central Nervous System Lymphoma

Providence Health & Services28 participantsStarted Mar 2024

New York, New York, United States • Cleveland, Ohio, United States • Portland, Oregon, United States +4 more locations

Active Not RecruitingPhase 236 miles

A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy

NCT05923866

This is a Phase 2, double-blind, parallel-group, placebo-controlled study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of multiple doses of ONO-2808 in patients with MSA. This is the first study of ONO-2808 in patients with MSA.

Multiple System Atrophy (MSA)

Ono Pharmaceutical Co. Ltd92 participantsStarted Sep 2023

Fountain Valley, California, United States • Los Angeles, California, United States • Los Angeles, California, United States +32 more locations

Maintenance Obinutuzumab in Treating Patients With Central Nervous System Lymphoma Who Have Achieved a Complete or Partial Response

A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy

Find Trials by Condition in Pennsylvania

Research Study To See How Well An Eye Drop (SURF-200) Works, What Side Effects There Are, And To Compare It With Vehicle In Subjects With An Episodic Flare-Up of Dry Eye Disease

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

Access MeMed BV Assay Clinical Study Collection Protocol - Infectious Adult and Pediatric Cohorts

Study to Assess the Safety, Tolerability, Pharmacokinetics and Immunogenicity of AK006 in Healthy Subjects and Subjects With Chronic Spontaneous Urticaria

A Study to Evaluate the Safety, Tolerability and Immunogenicity of EGFR(V)-EDV-Dox in Subjects With Recurrent GBM

Continuing Treatment for Participants Who Have Participated in a Prior Protocol Investigating Elotuzumab

A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 2 Diabetes Currently Treated With Basal Insulin

Assessment of Early Pregnancy MAB Completion

RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

Efficacy and Safety of GMRx2 Compared to Dual Combinations for the Treatment of Hypertension

Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

A Multi-Center Trial of Androgen Suppression With Abiraterone Acetate, Leuprolide, PARP Inhibition and Stereotactic Body Radiotherapy in Prostate Cancer

Atlas of Retinal Imaging in Alzheimer's Study

Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Disease

Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy