Clinical Trials in North Carolina

Showing 1221-1240 of 9,731 trials

Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP

NCT05308472

This is a Phase 2, multi-center, double-blind, placebo-controlled, parallel group study of bitopertin to evaluate the safety, tolerability, efficacy, and PPIX concentration change in participants with EPP. Participants may roll over to an open label extension portion after completing the double-blind treatment period.

Erythropoietic Protoporphyria

Disc Medicine, Inc75 participantsStarted Oct 2022

Birmingham, Alabama, United States • San Francisco, California, United States • Miami, Florida, United States +6 more locations

Active Not RecruitingPhase 241 miles

A Study of CT-388 in Participants Who Are Overweight or Obese With Type 2 Diabetes Mellitus

NCT06628362

This is a multi-center, randomized, double-blind, placebo-controlled, parallel group dose-finding study to evaluate the efficacy and safety of CT-388 at low, middle, and high doses in participants who are overweight or obese with Type 2 diabetes mellitus (T2DM).

Overweight or ObeseType 2 Diabetes Mellitus (T2DM)

Carmot Therapeutics, Inc.360 participantsStarted Nov 2024

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Guntersville, Alabama, United States +67 more locations

Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP

A Study of CT-388 in Participants Who Are Overweight or Obese With Type 2 Diabetes Mellitus

Find Trials by Condition in North Carolina

Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

[18F]PI-2620 Phase 3 Histopathological Study

Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial)

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus

The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma

Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors

A Study to Evaluate the Efficacy, Safety, and Tolerability of ASC30 Tablets in Participants With Type 2 Diabetes Mellitus

Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL

PoNS® Therapy for Gait and Balance Deficits in Chronic Stroke Survivors: A Single-Arm Study

Conservative Surgery in Treating Patients With Low-Risk Stage IA2 or IB1 Cervical Cancer

International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

A Study to Evaluate AI-09 In Participants With Glabellar Lines

Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD)

A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors

Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.