Clinical Trials in North Carolina

Showing 1201-1220 of 17,526 trials

Linezolid for Syphilis Pilot Study

NCT05548426

The study aims to evaluate the efficacy of linezolid for the treatment of syphilis.

University of Southern California24 participantsStarted Sep 2023

Chicago, Illinois, United States • Jackson, Mississippi, United States • Jackson, Mississippi, United States +2 more locations

RECRUITINGPhase 346 miles

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

NCT06264180

This is a randomized, controlled, multicenter, open-label Phase 3 clinical study comparing VO in combination with nivolumab versus Physician's Choice treatment for patients with unresectable Stage IIIb-IV cutaneous melanoma whose disease progressed on an anti PD-1 and an anti-CTLA-4 containing regimen (administered either as a combination regimen or in sequence) or who are not candidates for treatment with an anti-CTLA-4 therapy.

Advanced Melanoma

Replimune, Inc.400 participantsStarted Jul 2024

Gilbert, Arizona, United States • La Jolla, California, United States • Los Angeles, California, United States +70 more locations

Linezolid for Syphilis Pilot Study

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

Find Trials by Condition in North Carolina

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR)

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

A Study of Dotinurad Versus Allopurinol in Participants With Gout

Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder

A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

A Web-Based Tool to Help People With Health Conditions Make Contraceptive Decisions

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Study of AOC 1001 in Adult Myotonic Dystrophy Type 1 (DM1) Patients

Study Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous Urticaria

Optimizing Reperfusion to Improve Outcomes and Neurologic Function

CLEANer Aspiration for Pulmonary Embolism

Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)

A Multi-country, Cross-sectional Quantitative Study Exploring Awareness, Understanding, and Perceptions of the Relation Between Cardiorenal Metabolic Conditions and MASLD/MASH Among Healthcare Providers, People With MASLD/MASH, and At-risk Population

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

BGB-A3055 Alone and in Combination With Tislelizumab in Participants With Solid Tumors