Clinical Trials in North Carolina

Showing 11981-12000 of 17,526 trials

Exercise and Weight Loss for Improving Mobility in Older Adults Who Are Obese

NCT00119795

To test the effects of exercise and weight loss on mobility disability of older overweight/obese men and women who have evidence of cardiovascular disease or the metabolic syndrome.

Cardiovascular DiseasesHeart DiseasesMetabolic Syndrome X+1 more

Wake Forest University Health Sciences288 participantsStarted Aug 2005

Greensboro, North Carolina, United States • Lexington, North Carolina, United States • Winston-Salem, North Carolina, United States

COMPLETEDPhase 1/241 miles

A Study of Alectinib (CH5424802/RO5424802) in Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer (NSCLC)

NCT01871805

This non-randomized, open-label, multicenter study will evaluate the safety and efficacy of alectinib in participants with ALK-rearranged non-small cell lung cancer who failed crizotinib treatment. In Phase I, cohorts of participants will receive escalating doses of alectinib orally twice daily. In Phase II, patients who failed crizotinib treatment will receive the recommended phase II dose.

Non-Small Cell Lung Cancer

Hoffmann-La Roche134 participantsStarted Sep 2013

Birmingham, Alabama, United States • Irvine, California, United States • La Jolla, California, United States +39 more locations

Exercise and Weight Loss for Improving Mobility in Older Adults Who Are Obese

A Study of Alectinib (CH5424802/RO5424802) in Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer (NSCLC)

Find Trials by Condition in North Carolina

Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure

Predicting Acute Compartment Syndrome (PACS)

Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer

Supportive Intervention Programs Study

Development and Validation of a Quality of Life Instrument for Actinic Keratosis

SF1126 for Patients With Relapsed or Refractory Neuroblastoma

Transcranial Alternating Current Stimulation for Major Depressive Disorder

The POSAtive Study: Study for the Treatment of Positional Obstructive Sleep Apnea

A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE)

Study to Evaluate the Safety and Immune Response of Two-Doses of Candidate Influenza Vaccine GSK 1557484A in Adults

EINSTEIN Junior Phase II: Oral Rivaroxaban in Young Children With Venous Thrombosis

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

US-licensed Combined Vaccine Against Tetanus & Diphtheria, Given With US-licensed Vaccine Against Meningococcal Disease

Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma

Pharmacokinetics, Safety, and Efficacy of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate Single Tablet Regimen (STR) in Adolescents

Liposomal Doxorubicin Followed By Bexarotene in Treating Patients With Cutaneous T-Cell Lymphoma

Building Capacity for Sustainable Livelihoods and Health

Automated Screen for Fetal Aneuploidy