Clinical Trials in North Carolina

Showing 10761-10780 of 15,496 trials

Safety, Tolerability and Efficacy of ISIS-GCGRRx in Patients With Type 2 Diabetes

NCT02583919

The purpose of this study is to evaluate the efficacy, safety, and tolerability of ISIS-GCGRRx in combination with metformin versus placebo

Type 2 Diabetes

Ionis Pharmaceuticals, Inc.79 participantsStarted Sep 2015

Greenbrae, California, United States • Huntington Park, California, United States • La Mesa, California, United States +16 more locations

COMPLETEDPhase 241 miles

Docetaxel, Cisplatin, Pegfilgrastim, and Erlotinib Hydrochloride in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

NCT01557959

This phase II trial is studying how well docetaxel given together with cisplatin and pegfilgrastim followed by erlotinib hydrochloride works in treating patients with stage IIIB or stage IV non-small cell lung cancer. Drugs used in chemotherapy, such as docetaxel and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Colony stimulating factors, such as pegfilgrastim, may increase the number of immune cells found in bone marrow or peripheral blood and may help the immune system recover from the side effects of chemotherapy. Erlotinib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving dose-dense combination chemotherapy together with pegfilgrastim and erlotinib hydrochloride may kill more tumor cells

Adenocarcinoma of the LungAdenosquamous Cell Lung CancerBronchoalveolar Cell Lung Cancer+6 more

Wake Forest University Health Sciences45 participantsStarted Jul 2007

Winston-Salem, North Carolina, United States

Safety, Tolerability and Efficacy of ISIS-GCGRRx in Patients With Type 2 Diabetes

Docetaxel, Cisplatin, Pegfilgrastim, and Erlotinib Hydrochloride in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Find Trials by Condition in North Carolina

Risk Factors for Developing a Blood Clot in Patients Who Are Undergoing Cancer Treatment for Newly Diagnosed Gliomas

Rebif® Versus Copaxone® in the Treatment of Relapsing Remitting Multiple Sclerosis

Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Breast Augmentation

Innovative Tool to Increase Completion of Human Papillomavirus (HPV) Vaccine Series

Trial of Pregabalin for Granulocyte Colony-stimulating Factor (GCSF)-Induced Bone Pain

Multi-center, Randomized, Double-blind Efficacy and Safety of CD0271 0.3%/CD1579 2.5 % Topical Gel in Acne Vulgaris

COOL-ARREST Pilot Study to Assess Intravascular Temperature Management (IVTM) in the Treatment of Cardiac Arrest

Follow-up Study to Evaluate the Safety and Immunogenicity of a HPV Vaccine (580299) in North America

VenaSeal Sapheon Closure System Pivotal Study (VeClose)

Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma

Gefitinib in Treating Patients With Recurrent or Progressive CNS Tumors

Temozolomide Plus Thalidomide in Treating Patients With Recurrent or Progressive Brain Tumor

A Post-approval LAP-BAND® Lower Body Mass Index (LBMI) Study

Measuring the Impact of MammaPrint on Adjuvant and Neoadjuvant Treatment in Breast Cancer Patients: A Prospective Registry

Temozolomide and Carmustine in Treating Patients With Anaplastic Glioma

Safety and Tolerability Study of ISIS EIF4E Rx in Combination With Carboplatin and Paclitaxel

Predictive Markers in Growth Hormone Deficiency (GHD) and Turner Syndrome (TS) Children Treated With SAIZEN®

Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial