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COMPLETEDPhase 4NCT04169061

Impact of Acthar on Everyday Life of Participants With Severe Keratitis

We will need about 36 participants for this study. Volunteers might be able to participate if: * they have bad noninfectious keratitis * early treatments failed or were not well tolerated Participa...

Lead sponsor: Mallinckrodt•9 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Mallinckrodt

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Has severe or recalcitrant keratitis
•Did not respond to, or tolerate, treatment with topical cyclosporine, Lifitegrast, or any immunosuppressant to treat keratitis
•If able to reproduce, agrees to use 2 forms of effective contraception with a partner of the opposite sex for the duration of the study (through Visit 6)
•Has normal eyelids, and protocol-defined physical and medical eye attributes
•Agrees to avoid wearing contact lenses during the trial

Exclusion Criteria

•Is pregnant or breast-feeding
•Is defined as vulnerable, or is employed by, or related to anyone involved in the study
•Has a medical condition or history that might, per protocol or in the opinion of the investigator, compromise the participant's safety or study analysis

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: August 18, 2021Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE4

Enrollment36

Start dateNov 2019

Last updatedAug 18, 2021

Condition

Locations shown

Cornea and Cataract Consultants of Arizona

Phoenix, Arizona

Global Research Management, Inc.

Glendale, California

Eye Research Foundation

Newport Beach, California

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 18, 2021Data synced to Clareo: May 3, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions