Clinical Trials in North Carolina

Showing 9561-9580 of 20,428 trials

Prognosticating Outcomes and Nudging Decisions With Electronic Records in the ICU Trial

NCT03139838

This is a pragmatic, stepped-wedge, cluster randomized trial testing the real-world effectiveness of two different electronic health record (EHR) behavioral interventions in improving a number of patient- and family-centered processes and outcomes of care among seriously ill hospitalized patients. The investigators hypothesize that outcomes can be improved without raising costs by requiring intensive care unit clinicians to (i) document a prognostic estimate and (ii) provide a justification if they choose not to offer patients the option of comfort-oriented care. To test this hypothesis the investigators will conduct a 33-month trial at 17 intensive care units in 10 hospitals using the same Cerner EHR within Atrium Health System.

Critical Illness

University of Pennsylvania3,500 participantsStarted Feb 2018

Albemarle, North Carolina, United States • Charlotte, North Carolina, United States • Charlotte, North Carolina, United States +7 more locations

COMPLETED41 miles

Study to Assess the Effectiveness of AboBoNT-A Injections for Adult Lower Limb Spasticity in a Real Life Cohort

NCT04050527

The purpose of the protocol is to assess the longitudinal attainment of person-centered and function related goals of patients who receive AbobotulinumtoxinA (aboBoNT-A) injections for adult lower limb spasticity over a period of 16 months.

Adult Lower Limb Spasticity

Ipsen438 participantsStarted Dec 2019

Downey, California, United States • Washington D.C., District of Columbia, United States • Leawood, Kansas, United States +48 more locations

Prognosticating Outcomes and Nudging Decisions With Electronic Records in the ICU Trial

Study to Assess the Effectiveness of AboBoNT-A Injections for Adult Lower Limb Spasticity in a Real Life Cohort

Find Trials by Condition in North Carolina

FGF23 and Angiotensin-(1-7) in Hypophosphatemia (GAP)

Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer

Study of Biomarkers in Blood and Bone Marrow Samples From Patients With Previously Untreated Chronic Lymphocytic Leukemia

Genetics of Primary Ciliary Dyskinesia

Rare Genetic Disorders of the Breathing Airways

Pediatrician Wellbeing Program

Study of Nivolumab (BMS-936558) vs. Everolimus in Pre-Treated Advanced or Metastatic Clear-cell Renal Cell Carcinoma (CheckMate 025)

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Adolescents and Adults With Chronic Plaque Psoriasis

A Study to Evaluate the Safety and Efficacy of Nivolumab Monotherapy and Nivolumab in Combination With Ipilimumab in Pediatric Participants With High Grade Primary Central Nervous System (CNS) Malignancies

A Study of LY3561774 in Participants With Dyslipidemia

Safety of and Immune Response to a Prime-Boost Vaccine Regimen in HIV-Uninfected Vaccine-Naive Adults

Evaluating the Immunogenicity of the AIDSVAX B/E Vaccine and the MVA/HIV62B Vaccine in Healthy, HIV-1-Uninfected Adults Who Previously Received MVA/HIV62B in DNA/MVA or MVA/MVA Regimens in HVTN 205

Transdisciplinary Versus Usual Care for Type1 Diabetes in Adolescence

Salivary Profiling in Infants Treated for Suspected Sepsis: The SPITSS Study

Safety, Pharmacokinetics and Efficacy of ARQ-151 Cream in Adults With Mild to Moderate Chronic Plaque Psoriasis

Dalteparin and Sunitinib Malate as First-Line Therapy in Treating Patients With Kidney Cancer That is Metastatic or Cannot Be Removed by Surgery

Treatment for COVID-19 in High-Risk Adult Outpatients

Antibiotic Resistance in Global Pediatric Oncology Centers