Clinical Trials in North Carolina

Showing 7541-7560 of 20,428 trials

Ultrasound in Detecting Taxane-Induced Neuropathy in Patients With Breast Cancer

NCT03139435

This pilot clinical trial studies how well ultrasound works in detecting taxane-induced neuropathy in patients with breast cancer. Ultrasound may work better in diagnosing and detecting neuropathy in breast cancer patients treated with the chemotherapy drug called a taxane.

Peripheral NeuropathyStage 0 Breast CancerStage I Breast Cancer+10 more

Wake Forest University Health Sciences20 participantsStarted May 2017

Winston-Salem, North Carolina, United States

SUSPENDEDPhase 341 miles

Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma

NCT02546102

ICT-107 consists of dendritic cells, prepared from autologous mononuclear cells that are pulsed with six synthetic peptides that were derived from tumor associated antigens (TAA) present on glioblastoma tumor cells. This is a Phase 3 study to evaluate ICT-107 in patients with newly diagnosed glioblastoma. Subjects will be randomized to receive standard of care chemoradiation (temozolomide (TMZ) with either ICT-107 or a blinded control. Reinfusion with the pulsed dendritic cells should stimulate cytotoxic T cells to specifically target glioblastoma tumour cells.

Glioblastoma Multiforme

Precision Life Sciences Group234 participantsStarted Dec 2024

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Duarte, California, United States +62 more locations

Ultrasound in Detecting Taxane-Induced Neuropathy in Patients With Breast Cancer

Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma

Find Trials by Condition in North Carolina

DaxibotulinumtoxinA for Injection for the Management of Plantar Fasciitis

Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome (LAVENDER™)

TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)

A Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-112 Injection in Subjects With Advanced Solid Tumors and Subsequent Dose Expansion Cohorts

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease

An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-2)

Palbociclib (PD-0332991) Combined With Fulvestrant In Hormone Receptor+ HER2-Negative Metastatic Breast Cancer After Endocrine Failure (PALOMA-3)

Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain

A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD

Retrospective Evaluation of SuperSaturated Oxygen (SSO2) Therapy Clinical Utility

Spiration Valves Against Standard Therapy

A Biomarker Study in Advanced Mucosal or Acral Lentiginous Melanoma Receiving Nivolumab in Combination With Ipilimumab

An Open-Label, Single Arm Study of Obinutuzumab Short Duration Infusion in Patients With Previously Untreated Advanced Follicular Lymphoma

Study of AT-02 in Healthy Volunteers and Subjects With Systemic Amyloidosis

Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor ALL

Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors

Neoadjuvant and Adjuvant Checkpoint Blockade

A Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract