Clinical Trials in North Carolina

Showing 7521-7540 of 20,428 trials

Assessing Functional Status Needs Via PRO Measures for Pts With Metastatic Breast Cancer

NCT05755347

The purpose of this single-site non-randomized study is to identify areas of need related to functional status and overall health, including nutrition and mental health in subjects with metastatic breast cancer (MBC). A decline in functional status is observed after breast cancer diagnosis and exacerbated by treatment. Declining functional status impacts the quality of life and can lead to increased comorbidity burden, hospitalization, and increased mortality. Functional status is assessed by specific provider-graded scales. Patient Reported Outcome (PRO) measures may better assess certain aspects of patient health and symptom domains. Thus, potentially supporting the future implementation of effective prehabilitation strategies. This study explores whether a PRO-based survey will identify the physical and emotional health and the social and financial status of patients newly diagnosed with MBC.

Breast CancerMetastasis

UNC Lineberger Comprehensive Cancer Center50 participantsStarted Mar 2023

Chapel Hill, North Carolina, United States

COMPLETEDPhase 346 miles

Open-Label Extension Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome

NCT04279314

To investigate the safety and tolerability of long-term treatment with oral trofinetide in girls and women with Rett syndrome

Rett Syndrome

ACADIA Pharmaceuticals Inc.154 participantsStarted Jan 2020

Birmingham, Alabama, United States • Phoenix, Arizona, United States • La Jolla, California, United States +18 more locations

Assessing Functional Status Needs Via PRO Measures for Pts With Metastatic Breast Cancer

Open-Label Extension Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome

Find Trials by Condition in North Carolina

Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain

A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients

Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration

Study Evaluating Safety, Tolerability and Clinical Activity of GSK2857916 in Combination With Pembrolizumab in Subjects With Relapsed/Refractory Multiple Myeloma (RRMM)

The Pristine Post-Market Study

Evaluation of Product Performance of a New Silicone Hydrogel Multifocal Contact Lens

Safety and Effectiveness Study of the Zenflow Spring System

A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF)

Phase I/IIa Study of H002 in NSCLC With Active EGFR Mutation

Immunogenicity, Safety and Tolerability of the Typhoid Fever Vaccine Candidate M01ZH09 in Healthy Adults

A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa

A Maintenance Therapy Study of Odetiglucan With CDX-1140 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

A Study of Olaparib and Durvalumab in Prostate Cancer

Pilot Study to Examine the Feasibility of the Dynamic Interferential Spinal Cord Stimulation System™ (DISCSS™)

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O )

Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma

Study to Evaluate the Safety and Pharmacokinetics of Efmarodocokin Alfa in Combination With Standard of Care in Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Lyophilized Fecal Microbiome Transfer vs. Vancomycin Monotherapy for Primary Clostridioides Difficile Infection