Clinical Trials in North Carolina

Showing 6121-6140 of 15,496 trials

Tenofovir Rectal Douche to Prevent HIV Transmission Among Adolescents (ATN DREAM)

NCT04686279

ATN DREAM is an early phase-1, open label study to examine the safety, pharmacokinetics (PK), pharmacodynamics (PD), and acceptability of a one-dose tenofovir (TFV) medicated douche. The overall goal is to inform the design of an extended safety study of an on-demand and behaviorally congruent TFV douche to confer protection from HIV acquisition in an outpatient pre-RAI context

HIV/AIDSHIV Prevention

University of Pennsylvania8 participantsStarted Apr 2021

Atlanta, Georgia, United States • Baltimore, Maryland, United States • Chapel Hill, North Carolina, United States

COMPLETED46 miles

Molecular Phenotypes for Cystic Fibrosis Lung Disease

NCT01116414

The purpose of this study is to develop an integrated view of molecular mechanisms underlying CF lung disease severity.

Cystic FibrosisLung Diseases

University of North Carolina, Chapel Hill152 participantsStarted Jul 2009

Baltimore, Maryland, United States • Chapel Hill, North Carolina, United States • Cleveland, Ohio, United States

TERMINATED46 miles

A Prospective Study to Evaluate the ConforMIS iTotal® (PS) Knee Replacement System

NCT03152162

This is a prospective clinical study designed to observe the long-term clinical outcomes of total knee arthroplasty using a patient-specific, posterior stabilized implant in patients with osteoarthritis.

Osteoarthritis, Knee

Restor3D102 participantsStarted May 2017

Chapel Hill, North Carolina, United States • Austin, Texas, United States • Morrisville, Vermont, United States +1 more locations

Tenofovir Rectal Douche to Prevent HIV Transmission Among Adolescents (ATN DREAM)

Molecular Phenotypes for Cystic Fibrosis Lung Disease

A Prospective Study to Evaluate the ConforMIS iTotal® (PS) Knee Replacement System

Find Trials by Condition in North Carolina

Safety and Efficacy Study of AVB-S6-500 (Batiraxcept) in Patients With Advanced Pancreatic Adenocarcinoma

Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma

Safety and Tolerability Study Of PF-06835375 In Subjects With Seropositive Systemic Lupus Erythematosus Or Rheumatoid Arthritis

Trial to Evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory Myopathy

A Study of mRNA-1010 Seasonal Influenza Vaccine in Healthy Adults

A Study to Compare the Efficacy of Arfolitixorin Versus Leucovorin in Combination With 5 Fluorouracil, Oxaliplatin, and Bevacizumab in Patients With Advanced Colorectal Cancer

Volume Optimization Incorporating Negative Pressure Diuresis in Heart Failure (VOID-HF)

A Study to Evaluate the Conformis Hip System

Identification of Clinically Insignificant or Significant Prostate Cancer With the miR Scientific Sentinel™ Platform

The Chocolate Touch Study

A Study to Investigate Atezolizumab and Chemotherapy Compared With Placebo and Chemotherapy in the Neoadjuvant Setting in Participants With Early Stage Triple Negative Breast Cancer

Multi-Center Study to Evaluate the ConforMIS iUni Knee Implant

A Study Evaluating the Safety, Pharmacokinetics and Efficacy of Ipatasertib Administered in Combination With Rucaparib in Participants With Advanced Breast, Ovarian Cancer, and Prostate Cancer.

A Prospective, Multicenter Study to Evaluate the ConforMIS iTotal® (CR) Knee Replacement System

A Study to Evaluate the Conformis iTotal Identity Knee Replacement System

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal

Study of the ConforMIS iDuo(R) G2