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Clinical TrialsNorth Carolina

Clinical Trials in North Carolina

Discover 5,175 clinical trials near North Carolina. Find research studies in your area.

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma Pancreatic Cancer

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 41-60 of 5,175 trials

Completed"MyPlan" - Individualized Planned Eating Patterns for Adolescents With Type 1 DiabetesThe purpose of this study is to test the acceptability and effectiveness of an individualized eating strategy as part of diabetes self-management to improve glycemic levels among…NCT05147324·Chapel Hill, North Carolina and 1 other CompletedEfficacy, Safety and Immunogenicity of Takeda's Tetravalent Dengue Vaccine (TDV) in Healthy ChildrenThe main purpose of this study is to evaluate the efficacy of 2 doses of Tetravalent Dengue Vaccine Candidate (TDV) in preventing symptomatic dengue fever of any severity and due…NCT02747927·Vitória, Espírito Santo and 27 others

Find Trials by Condition in North Carolina

Breast Cancerin North Carolina Lung Cancerin North Carolina Prostate Cancerin North Carolina Colorectal Cancerin North Carolina Melanomain North Carolina Leukemiain North Carolina Lymphomain North Carolina Pancreatic Cancerin North Carolina Ovarian Cancerin North Carolina Brain Cancerin North Carolina

Data from ClinicalTrials.govTerms

Active not recruitingA Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic AtrophyThis study is for people who have geographic atrophy due to age-related macular degeneration (AMD).NCT06779773·Phoenix, Arizona and 57 others

CompletedA Transgenerational e-Intervention for Gestational Diabetics and Their OffspringThis study includes a behavioral educational intervention that focuses on healthy eating, physical activity and glucose management during pregnancy and post partum among women…NCT01931280·Chapel Hill, North Carolina

RecruitingEvolutionary Clinical Trial for Novel Biomarker-Driven TherapiesThis is a multicenter, multi-arm, biomarker-stratified trial designed to evaluate biomarker-directed therapies in patients with estrogen receptor-positive/hormone…NCT07340541·New Haven, Connecticut and 5 others

CompletedTesting the Addition of a New Anti-Cancer Drug, Niraparib, to the Usual Treatment (Hormone and Radiation Therapy) for Prostate Cancer With a High Chance of RecurringThis is a phase I-II trial to find the safety and activity of adding a new drug (neraparib) to the usual treatment (radiation combined with male hormone deprivation therapy) in…NCT04037254·Gilbert, Arizona and 94 others

CompletedVincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk RhabdomyosarcomaThis phase III trial is studying how well combination chemotherapy and radiation therapy work in treating patients with newly diagnosed low-risk rhabdomyosarcoma.NCT00075582·Birmingham, Alabama and 162 others

CompletedA Study of Two Anti-HIV Drug CombinationsThe purpose of this study is to compare the safety and effectiveness of taking lamivudine (3TC) plus zidovudine (ZDV) plus a protease inhibitor (PI) with taking the 3TC/ZDV…NCT00002203·Beverly Hills, California and 6 others

CompletedCarboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast CancerThis randomized phase II trial studies how well carboplatin with or without atezolizumab works in treating patients with stage IV triple negative breast cancer.NCT03206203·Washington D.C., District of Columbia and 5 others

CompletedMulti-component Family Support Tool Intervention (FST)The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die…NCT05019261·Springfield, Massachusetts and 6 others

CompletedSPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating DisorderThe primary objective of the study is to demonstrate the efficacy of SPD489 compared with placebo in adults (18 55 years of age inclusive) with moderate to severe Binge Eating…NCT01718483·Birmingham, Alabama and 49 others

Active not recruitingA Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK InhibitorThis is a parallel group, Phase 3, multinational, multicenter, randomized, double-blind, placebo-controlled, 3-arm study for treatment of participants diagnosed with…NCT06241118·Birmingham, Alabama and 153 others

CompletedDose Finding Study of Gadavist in Central Nervous System (CNS) Magnetic Resonance Imaging (MRI)The purpose of this study is to look at the safety (what are the side effects) and efficacy (how well does it work) of Gadavist when used for taking images of the brain and spine.NCT00862459·Sacramento, California and 26 others

RecruitingFrontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple MyelomaThis is an open-label, multi-site, Phase II randomized trial with response-adaptive design for newly diagnosed multiple myeloma (NDMM) participants who have had prior induction…NCT06974786·Birmingham, Alabama and 10 others

CompletedThe EPIC Observational StudyThe purpose of this study is to better define risk factors preceding first isolation of Pseudomonas aeruginosa (Pa) from respiratory cultures in cystic fibrosis (CF) lung disease…NCT00676169·Birmingham, Alabama and 53 others

RecruitingTesting the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)This phase II MyeloMATCH treatment trial compares the usual treatment of cedazuridine-decitabine (ASTX727) to the combination treatment of ASTX727 and enasidenib in treating…NCT06577441·Berkeley, California and 150 others

Active not recruitingTesting the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 NegativeThis phase II/III trial compares the addition of radiation therapy to the usual treatment (immunotherapy with or without chemotherapy) versus (vs.) usual treatment alone in…NCT04929041·Phoenix, Arizona and 168 others

Not yet recruitingEvaluating Narrative Vaping Prevention Video Ads for Adolescents and Young AdultsThe purpose of this study is to evaluate the persuasive effectiveness of narrative advertisements: with acted-out plots (where characters enact a vaping-related experience) versus…NCT07767929·Fairfield, Connecticut and 1 other

TerminatedA Study to Evaluate the Efficacy and Safety of VX-765 in Subjects With Treatment-Resistant Partial EpilepsyThe purpose of this study is to evaluate the efficacy, safety and tolerability of VX-765 in subjects with treatment-resistant partial epilepsy.NCT01501383·Northport, Alabama and 23 others

CompletedAvoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain MetastasesRATIONALE: Radiation therapy uses high energy x-rays to kill tumor cells.NCT01227954·Birmingham, Alabama and 62 others

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