Clinical Trials in North Carolina

Showing 5321-5340 of 20,428 trials

Promoting Shared Decision Making for Severe Aortic Stenosis

NCT06171737

The goal of this study is to increase shared decision making for patients considering treatment for severe aortic stenosis. The main questions it aims to answer are: * Do patient decision aids and clinician skills training course improve the quality of decisions, and do they work well for different patient populations? * Are heart clinics able to reach the majority of patients with decision aids before their specialist visit and do the majority of clinicians complete the training course? All participating sites will start in the usual care group and then will be randomly assigned a time to switch to the intervention group. Participants will complete surveys before and after their specialist visit. Researchers will compare data from patients seen during usual care with data from those seen after the interventions are implemented to see if there are improvements in the quality of decisions.

Aortic Stenosis

Massachusetts General Hospital1,300 participantsStarted Mar 2024

San Francisco, California, United States • Aurora, Colorado, United States • Atlanta, Georgia, United States +5 more locations

TERMINATEDNA46 miles

Examining the Effects of Neuromodulation on Glucose Metabolism in Type 2 Diabetes

NCT02130401

This is an open-label, proof of concept study with a single active treatment arm designed to assess whether CVS-based stimulation has a beneficial effect on patients with type 2 diabetes. The primary outcome measure is a difference between pre and post-treatment A1c.

Type 2 Diabetes

Scion NeuroStim6 participantsStarted Jun 2014

Chapel Hill, North Carolina, United States

Promoting Shared Decision Making for Severe Aortic Stenosis

Examining the Effects of Neuromodulation on Glucose Metabolism in Type 2 Diabetes

Find Trials by Condition in North Carolina

Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)

Medical Access Program for Patritumab Deruxtecan

Pomalidomide in Combination With Low-dose Dexamethasone or Pomalidomide in Combination With Low-dose Dexamethasone and Daratumumab in Subjects With Relapsed or Refractory Multiple Myeloma Following Lenalidomide-based Therapy in the First or Second Line Setting

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

Customized Employment for Veterans With Spinal Cord Injury

D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)

Study of Safety and Efficacy of Pembrolizumab and Chemotherapy in Participants With Newly Diagnosed Classical Hodgkin Lymphoma (cHL) (MK-3475-C11/KEYNOTE-C11)

TAC T-cells for the Treatment of HER2-positive Solid Tumors

Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6

Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors

A Study ATG-101 in Patients With Metastatic/Advanced Solid Tumors and Mature B-cell Non-Hodgkin Lymphomas

Understanding the Natural History Early in the Course or Presentation of Friedreich Ataxia

Study to Evaluate Safety and Immunogenicity of a Prime-Boost Regimen of rVSV-Nipah Virus Vaccine Candidate PHV02 in Healthy Adult Subjects

A COVID-19 Study to Evaluate Safety and PK of COVID-HIG Administered Through IM, SC, or IV Routes to SARS-CoV-2 Uninfected Adults

A Study Evaluating the Safety and Efficacy of MINIject S+ in Subjects With Open Angle Glaucoma