Clinical Trials in North Carolina

Showing 3201-3220 of 20,428 trials

Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)

NCT02702869

The Allied Cleft \& Craniofacial Quality-Improvement and Research Network (ACCQUIREnet) is a group of multidisciplinary cleft teams that have implemented a system for prospective collection of outcomes data, based on the ICHOM Standard Set for the Comprehensive Appraisal of Cleft Care, CLEFT-Q, and other outcomes instruments. Participating cleft teams may analyze clinical and psychosocial outcomes related to care of the child with cleft lip and/or palate (CL/P), compare its performance with those of other cleft centers, and identify opportunities for quality improvement.

Cleft LipCleft PalateCleft Lip and Palate

Duke University1,000 participantsStarted Oct 2016

Gainesville, Florida, United States • Hollywood, Florida, United States • Orlando, Florida, United States +8 more locations

COMPLETEDPhase 341 miles

Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)

NCT04458051

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary Objectives: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety and tolerability of SAR442168 To evaluate population pharmacokinetics (PK) of SAR442168 in PPMS and its relationship to efficacy and safety To evaluate pharmacodynamics of SAR442168

Primary Progressive Multiple Sclerosis

Sanofi767 participantsStarted Aug 2020

La Jolla, California, United States • Los Alamitos, California, United States • Los Angeles, California, United States +274 more locations

Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)

Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)

Find Trials by Condition in North Carolina

Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

[18F]PI-2620 Phase 3 Histopathological Study

Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial)

Combo of Cabozantinib With Abiraterone in Chemotherapy-Naïve Subjects With Bone-Metastatic CRPC

The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma

A Study to Evaluate the Efficacy, Safety, and Tolerability of ASC30 Tablets in Participants With Type 2 Diabetes Mellitus

Use of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility Study

Molgramostim Nebulizer Solution Expanded Access Program Protocol

International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

Conservative Surgery in Treating Patients With Low-Risk Stage IA2 or IB1 Cervical Cancer

Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

A Study to Evaluate AI-09 In Participants With Glabellar Lines

A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)

A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors