Clinical Trials in North Carolina

Showing 2801-2820 of 20,428 trials

Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)

NCT06983041

The objective of this study is to determine clinical cure rate and safety of a proprietary Vaginal Cooling Device (VCD) in women with VCC. In addition, the safety, mycological cure rates, the speed and efficacy of symptom resolution, vaginal hyphae and polymorphonuclear (PMN) scores, and Quality-of-Life (QoL) parameters will be determined.

Vulvovaginal Candidiasis (VVC)Yeast Vaginitis

Coologics, Inc55 participantsStarted May 2025

Jacksonville, Florida, United States • Miami, Florida, United States • Smyrna, Georgia, United States +7 more locations

RECRUITINGPhase 146 miles

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

NCT05929235

The goal of this clinical trial is to study the safety and tolerability in all advanced solid tumors, including advanced urothelial carcinoma. The main question\[s\] it aims to answer are: * Is FX-909 safe and tolerable, as a monotherapy and in combination with Pembrolizumab * What is the right dose level for patients Participants will be asked to take FX-909 daily in tablet form, or FX-909 daily and Pembrolizumab every 3 weeks, and record any outcomes from taking the drug. Participants will also be asked to return for multiple site visits for various blood tests and to collect blood and tumor samples as well as have regular CT/MRI scans.

Advanced Urothelial CarcinomaOral Drug AdministrationOpen Label

Flare Therapeutics Inc.120 participantsStarted Aug 2023

San Francisco, California, United States • New Haven, Connecticut, United States • Chicago, Illinois, United States +8 more locations

Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

Find Trials by Condition in North Carolina

ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer

The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women

PK/PD of Digoxin in Infants With SVHD

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

Integrated Therapies for Alcohol Use in Alcohol-associated Liver Disease (ITAALD) Trial

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

A Study of PHN-010 in Patients With Advanced Solid Tumors

A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China

Study to Compare Efficacy, Safety, and Immunogenicity of LUBT010 (Proposed Ranibizumab Biosimilar) and Lucentis® in Patients With Neovascular AMD

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache

BCL2i CLAG-M in R/R Acute Myeloid Leukemia

R-3750 in Patients With Mild to Moderate Ulcerative Colitis

Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)