Study of Low Adherent Dressing Versus the Standard of Care for the Management of Skin Grafts Over Thermal Burns

Exclusion Criteria

• •Patients with electrical or chemical burns.
• •Patients with a study burn site excised and "grafted" with Integra.
• •Patients with study burn sites on the buttocks, scalp, hands, feet, neck or ears.
• •Patients taking vasopressors or inotropes.
• •Patients using systemic immunosuppressants (e.g., corticosteroids and anti-neoplastic agents, etc.).
• •Patients with acute renal failure, defined as creatinine clearance (CrCL) \>2.5 mg/dL or AKIN score greater than or equal to 2 or estimated GFR \< 30, if the assessment is conducted as part of the patient's routine clinical care.
• •Patients with acute respiratory distress syndrome (ARDS), if the assessment is conducted as part of the patient's routine clinical care.
• •Patients with liver cirrhosis (Childs-Pugh B Class or greater) or who have AST / ALT levels greater than or equal to 2 times the upper limit of theinstitution's normal range, if the assessment is conducted as part of the patient's routine clinical care.
• •Patients with a known sensitivity or known intolerance to mafenide acetate (Sulfamylon) or to silver.
• •Patients with any concurrent medical condition, which in the opinion of the investigator, may compromise their safety or the objectives of the study.
• •Patients who are breastfeeding, pregnant or expecting to become pregnant during the study..
• •Patients who have been exposed to an investigational drug or device within 30 days prior to Screening or is scheduled to receive another investigational drug or device during either the Treatment Phase or Follow-up Evaluation.