Clinical Trials in North Carolina

Showing 2341-2360 of 9,731 trials

Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm

NCT04026776

The purpose of this research is to learn about how salt in the diet influences blood pressure in young adults who were born prematurely.

Salt; ExcessBlood Pressure Disorders

Wake Forest University Health Sciences120 participantsStarted Sep 2020

Winston-Salem, North Carolina, United States

RECRUITING41 miles

Conversations You Want About Corona Virus Disease (COVID-19)

NCT05191420

Web-enabled virtual topical guide: develop virtual conversations for each concern and intensity level

Covid19

Wake Forest University Health Sciences23,000 participantsStarted Mar 2022

Winston-Salem, North Carolina, United States

RECRUITINGEARLY Phase 146 miles

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

NCT04139304

This feasibility trial studies how well daratumumab in combination with dose-adjusted etoposide, prednisone, vincristine sulfate, cyclophosphamide, and doxorubicin hydrochloride (DA-EPOCH) works in treating patients with newly diagnosed stage I-IV plasmablastic lymphoma. Plasmablastic lymphoma cells have high levels of a protein called CD38. Daratumumab is a monoclonal antibody that specifically targets CD38 expressing cells, and may help the body's immune system attack the cancer and interfere with the ability of cancer cells to grow and spread. Drugs used in chemotherapy, such as etoposide, prednisone, vincristine sulfate, cyclophosphamide, and doxorubicin hydrochloride, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving daratumumab may enhance the effectiveness of a standard chemotherapy (DA-EPOCH) in patients with plasmablastic lymphoma.

Plasmablastic LymphomaAnn Arbor Stage I Diffuse Large B-Cell LymphomaAnn Arbor Stage II Diffuse Large B-Cell Lymphoma+2 more

AIDS Malignancy Consortium15 participantsStarted May 2021

Miami, Florida, United States • Chicago, Illinois, United States • Baltimore, Maryland, United States +5 more locations

Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm

Conversations You Want About Corona Virus Disease (COVID-19)

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Find Trials by Condition in North Carolina

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)

Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

Trial to Evaluate the Safety and Pharmacokinetics of HMPL-689 in Patients With Lymphomas

Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma

Proliposomal Intravesical Paclitaxel for Treatment of Low-Grade, Stage Ta, Non Muscle Invasive Bladder Cancer

Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)

Study of ASN51 in Adults With Early Alzheimer's Disease

A Study of NPX887 for Participants With Solid Tumors Known to Express B7-H7/HHLA2

1630GCC: Zydelig Maintenance in B-Cell Non-Hodgkin's Lymphoma After Autologous Stem Cell Transplantation

DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

Gluten Technology and Education for Celiac Health

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors

FS120 Phase 1/1b Study in Patients With Advanced Malignancies

Cough Reduction in IPF With Nalbuphine ER