Clinical Trials in New York

Showing 17221-17240 of 22,668 trials

Treatment of Actinic Keratoses (AK) on the Face

NCT02411851

Actinic keratoses (AK) are common cutaneous lesions associate with chronic ultraviolet radiation exposure. While most authorities consider AK as a pre-malignant lesion, some consider it as an incipient squamous cell carcinoma (SCC). Ingenol mebutate is the active compound in the sap from Euphorbia peplus L. (E. peplus). Topical ingenol mebutate treatment has been approved for the treatment of AKs. Ingenol mebutate gel 0.015% has shown to not only have a high clearance rate but also a transient localized inflammatory skin response that resolves quickly without sequelae. However, these localized skin responses (eg erythema, erosion/ulceration, edema, etc.) can often be unpleasant and unsightly. Currently, there are no clinical studies evaluating combination therapies (eg topical steroids, emollients) with ingenol mebutate 0.015% that would decrease irritation and improve wound healing while maintaining efficacy.

Actinic Keratoses

Icahn School of Medicine at Mount Sinai20 participantsStarted Mar 2015

New York, New York, United States

COMPLETEDPhase 1< 1 mile

Safety and Tolerability Study of rAvPAL-PEG to Treat Phenylketonuria

NCT00634660

The purpose of this study is to assess the safety and tolerability of injections of rAvPAL-PEG in subjects with PKU.

Phenylketonuria

BioMarin Pharmaceutical25 participantsStarted May 2008

Chicago, Illinois, United States • Minneapolis, Minnesota, United States • St Louis, Missouri, United States +5 more locations

Treatment of Actinic Keratoses (AK) on the Face

Safety and Tolerability Study of rAvPAL-PEG to Treat Phenylketonuria

Find Trials by Condition in New York

A Study of Belimumab in Subjects With Systemic Lupus Erythematosus

Development of Melt Organic Baking Fat for Reducing Child Obesity

A Phase 1/2 Study of High-dose Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure

Early Conversion From CNI to Belatacept in Renal Transplant Recipients With Delayed and Slow Graft Function

Minocycline for Bipolar Depression

Role of Vascular Endothelial Growth Factor (VEGF) in Acute Lung Injury/Adult Respiratory Distress Syndrome (ARDS)

Text Message Vaccine Reminders for Adolescents With Chronic Medical Conditions

Assessment of Intrahepatic Hepatitis C Virus (HCV) RNA Levels at the Time of Liver Transplantation

Novel Epothilone (BMS-247550) in Patients With Metastatic Breast Cancer (MBC)

Giant Axonal Neuropathy Natural History Study

Rituximab, Lenalidomide, and Bortezomib in Mantle Cell Lymphoma

Long Duration Therapeutic Ultrasound for Tendon Healing

Long Duration Therapeutic Ultrasound on Tendon Injuries

CANagliflozin Treatment And Trial Analysis-Sulfonylurea (CANTATA-SU) SGLT2 Add-on to Metformin Versus Glimepiride

Evaluating the Safety and Immunogenicity of a Live Attenuated West Nile Virus Vaccine for West Nile Encephalitis in Adults 50 to 65 Years of Age

PT003 MDI Cardiovascular Safety Study

A Study of Intermittent, High-dose Afatinib to Determine the Maximal Tolerated Dose and Assess Activity of This Dose Against Non-small Cell Lung Cancer With T790M Mutations

A Study to Evaluate Cardiovascular Outcomes in Patients With Type 2 Diabetes Treated With ITCA 650