Clinical Trials in New York

Showing 16761-16780 of 22,668 trials

A Phase 1b Study to Assess the Safety and Anti-inflammatory Effects of Two Different Doses of SRT2104 in Patients With Ulcerative Colitis

NCT01453491

The purpose of this research study is to: * 1\) Test the safety and tolerability of 2 different oral doses of SRT2104 in subjects with ulcerative colitis * 2\) Determine the amount of SRT2104 measured from a single blood sample in addition to colon and/or rectal tissue samples (biopsies) * 3\) Determine whether SRT2104 has any anti-inflammatory effect on the colon and/or rectum when taken orally for 8 weeks * 4\) Determine whether SRT2104 causes any detectable changes to specific biomarkers. A biomarker is a biological marker (or substance such as a protein) that is used as an indicator of changes in a biological state that corresponds to the risk or progression of a disease.

Colitis, Ulcerative

Sirtris, a GSK Company17 participantsStarted Feb 2012

Anaheim, California, United States • Bristol, Connecticut, United States • Owensboro, Kentucky, United States +10 more locations

COMPLETEDPhase 1< 1 mile

A Multicenter, Open-label, Phase 1b Study of Carfilzomib, Cyclophosphamide and Dexamethasone in Newly Diagnosed Multiple Myeloma Subjects

NCT01980589

The primary objective was to determine the maximum tolerated dose of carfilzomib given twice weekly in combination with cyclophosphamide and dexamethasone for patients with newly diagnosed multiple myeloma.

Multiple Myeloma

Amgen22 participantsStarted Aug 2013

Encinitas, California, United States • West Hollywood, California, United States • Whittier, California, United States +6 more locations

A Phase 1b Study to Assess the Safety and Anti-inflammatory Effects of Two Different Doses of SRT2104 in Patients With Ulcerative Colitis

A Multicenter, Open-label, Phase 1b Study of Carfilzomib, Cyclophosphamide and Dexamethasone in Newly Diagnosed Multiple Myeloma Subjects

Find Trials by Condition in New York

A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease Therapy

Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's Esophagus

Preventative Omalizumab or Step-up Therapy for Severe Fall Exacerbations

Alpha-lipoic Acid/L-acetyl Carnitine for Progressive Supranuclear Palsy

An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome

GW873140 In Combination With Combivir In HIV Infected Subjects

A Bioequivalence Study of Two Oral Formulations of Topotecan in Patients With Advanced Solid Tumors

A Phase II Trial of Ofatumumab in Subjects With Waldenstrom's Macroglobulinemia

Investigation of How Morning Nutrition Influences Cognitive Performance

Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation

Terbinafine Compared to Griseofulvin in Children With Tinea Capitis

Monitoring Disease Activity Using Video Capsule Endoscopy (VCE) in Crohn's Disease (CD) Subjects

Lethargic Depression Study

A Phase 2, Multicenter, Open-label Study of MEDI-551 in Adults With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

Pivotal, Multicenter, Observer-Blind, Randomized Study of Influenza A (H1N1)2009 Monovalent Subunit Vaccine With and Without Adjuvant in Children Ages 6 to <36 Months

Observational Study Of A Protease Inhibitor (PI) Containing Regimen In Subjects With PI Mutations Selected During Prior Treatment With GW433908 (Fosamprenavir)

A Long Term Safety Study of Mavrilimumab in Adult Subjects With Rheumatoid Arthritis

BOTOX® Efficacy and Safety in the Treatment of Knee Osteoarthritis