Clinical Trials in New York

Showing 16761-16780 of 22,668 trials

A Phase 1b Study to Assess the Safety and Anti-inflammatory Effects of Two Different Doses of SRT2104 in Patients With Ulcerative Colitis

NCT01453491

The purpose of this research study is to: * 1\) Test the safety and tolerability of 2 different oral doses of SRT2104 in subjects with ulcerative colitis * 2\) Determine the amount of SRT2104 measured from a single blood sample in addition to colon and/or rectal tissue samples (biopsies) * 3\) Determine whether SRT2104 has any anti-inflammatory effect on the colon and/or rectum when taken orally for 8 weeks * 4\) Determine whether SRT2104 causes any detectable changes to specific biomarkers. A biomarker is a biological marker (or substance such as a protein) that is used as an indicator of changes in a biological state that corresponds to the risk or progression of a disease.

Colitis, Ulcerative

Sirtris, a GSK Company17 participantsStarted Feb 2012

Anaheim, California, United States • Bristol, Connecticut, United States • Owensboro, Kentucky, United States +10 more locations

COMPLETEDPhase 2< 1 mile

A Phase II Trial of Ofatumumab in Subjects With Waldenstrom's Macroglobulinemia

NCT00811733

Given the tolerability and efficacy of ofatumumab in follicular lymphoma and Chronic Lymphocytic Leukemia, and the need to improve therapy for patients with WM utilizing a non-myelosuppressive agent this phase II trial of ofatumumab is being initiated in patients with Waldenstrom's Macroglobulinemia (WM).

Waldenstrom Macroglobulinaemia

GlaxoSmithKline37 participantsStarted Mar 2009

Los Angeles, California, United States • Stanford, California, United States • Rochester, Minnesota, United States +4 more locations

A Phase 1b Study to Assess the Safety and Anti-inflammatory Effects of Two Different Doses of SRT2104 in Patients With Ulcerative Colitis

A Phase II Trial of Ofatumumab in Subjects With Waldenstrom's Macroglobulinemia

Find Trials by Condition in New York

A Multicenter, Open-label, Phase 1b Study of Carfilzomib, Cyclophosphamide and Dexamethasone in Newly Diagnosed Multiple Myeloma Subjects

Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's Esophagus

Phase 1b Multicenter Study of Carfilzomib With Lenalidomide and Dexamethasone in Relapsed Multiple Myeloma

An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome

Preventative Omalizumab or Step-up Therapy for Severe Fall Exacerbations

GW873140 In Combination With Combivir In HIV Infected Subjects

Sexual Functioning Study With Antidepressants

A Prospective Study to Collect High-Quality Documentation of Bleeds, Health-Related Quality of Life (HRQoL), and Safety Outcomes in Patients With Hemophilia A Treated With Standard-of-Care Treatment

Investigation of How Morning Nutrition Influences Cognitive Performance

Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation

Terbinafine Compared to Griseofulvin in Children With Tinea Capitis

Monitoring Disease Activity Using Video Capsule Endoscopy (VCE) in Crohn's Disease (CD) Subjects

Lethargic Depression Study

A Phase 2, Multicenter, Open-label Study of MEDI-551 in Adults With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

Pivotal, Multicenter, Observer-Blind, Randomized Study of Influenza A (H1N1)2009 Monovalent Subunit Vaccine With and Without Adjuvant in Children Ages 6 to <36 Months

A Long Term Safety Study of Mavrilimumab in Adult Subjects With Rheumatoid Arthritis

Efficacy, Safety and Evolution of Cardiovascular Parameters in Renal Transplant Recipients

BOTOX® Efficacy and Safety in the Treatment of Knee Osteoarthritis