Clinical Trials in New York

Showing 4761-4780 of 22,668 trials

Anti-viral Therapy in Alzheimer's Disease

NCT03282916

Anti-viral therapy in Alzheimer's disease will investigate the efficacy of treating patients with mild Alzheimer's disease with the U.S.A marketed generic anti-viral drug Valtrex (valacyclovir, 500mg oral tablet). Valacyclovir, titrated to 4 grams per day, repurposed to treat Alzheimer's disease, will be compared to matching placebo in the treatment of 130 mild AD patients (65 valacyclovir, 65 placebo) who test positive for herpes simplex virus-1 (HSV1) or herpes simplex virus-2 (HSV2). The study will be a randomized, double-blind, 18-month Phase II proof of concept trial.

Alzheimer DiseaseHerpes Simplex 1Herpes Simplex 2

Columbia University120 participantsStarted Feb 2018

Phoenix, Arizona, United States • New York, New York, United States • New York, New York, United States

RECRUITINGNA< 1 mile

Engage & Connect: A Psychotherapy for Postpartum Depression

NCT05585164

This randomized controlled trial compares a novel psychotherapy, Engage \& Connect, with a Symptom Review and Psychoeducation intervention, tailored to reduce postpartum depression. The study includes 9-weeks interventions, delivered remotely. It will examine changes in social isolation, processing of social rewards and depression severity over 9 weeks of treatment.

Postpartum Depression

Weill Medical College of Cornell University60 participantsStarted Nov 2022

New York, New York, United States

Anti-viral Therapy in Alzheimer's Disease

Engage & Connect: A Psychotherapy for Postpartum Depression

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Technology-Based Intervention Usability and Pilot Testing

Mobile Ostomates Resources for Patients and Caregivers

Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

Local Methotrexate Injections for the Treatment of Nail Psoriasis

A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation

PENG vs. FIC Block for Hip Fracture ED Patients

ENCALM: A Study of ENX-102 as a Monotherapy Treatment in Patients With Generalized Anxiety Disorder

Reducing Burden in Care Partners of Community-Dwelling Persons With Dementia and Oropharyngeal Dysphagia

Air Pollution Study: The Effect of Ozone on the Lung

A Study of Cabozantinib Compared With Placebo in Subjects With Radioiodine-refractory Differentiated Thyroid Cancer Who Have Progressed After Prior Vascular Endothelial Growth Factor Receptor (VEGFR) -Targeted Therapy

An Observational Registry of Abatacept in Patients With Juvenile Idiopathic Arthritis

First In Human Study With ABBV-CLS-579 When Given Alone and In Combination In Participants With Locally Advanced Or Metastatic Tumors

Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

Beta-Agonist Versus OnabotulinumtoxinA Trial for Urgency Urinary Incontinence

Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)

To Assess the Pharmacokinetics and Safety and Tolerability of Efanesoctocog Alfa (BIVV001)in Adults With Type 2N and 3 Von Willebrand Disease (VWD)

Nitric Oxide Nasal Spray (NONS) as Prevention for Treatment of Individuals at Risk of Exposure to COVID-19 Infection

A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis