Clinical Trials in New York

Showing 21721-21740 of 22,668 trials

Phase I Study of U3P1287/01, Including Patients With Advanced Solid Tumors

NCT00730470

This is a Phase 1 clinical study to investigate the safety, pharmacokinetics, and pharmacodynamics of U3-1287 (AMG 888), a fully human monoclonal antibody targeting the HER3 receptor, in patients with advanced solid tumors. Eligible patients will have disease that is refractory or resistant to standard treatments or for which no standard therapy exists. The study will be conducted in two parts; a dose escalation (Part 1) and a dose expansion (Part 2). The hypothesis for this study is that U3-1287 (AMG888) will be safe and well tolerated in patients with advanced solid tumors and will show initial evidence of anti-tumor activity.

Advanced Solid Tumors

U3 Pharma GmbH60 participantsStarted Aug 2008

Boston, Massachusetts, United States • Boston, Massachusetts, United States • Detroit, Michigan, United States +3 more locations

COMPLETEDPhase 4< 1 mile

Open-Label Safety Study to Evaluate Imiquimod Cream, 5% for Large Areas of Actinic Keratosis

NCT00116649

Actinic keratosis (AK) is a skin condition that shows up on skin routinely exposed to the sun, such as the face, scalp, shoulders, chest, back, arms, and hands. The purpose of this study is to evaluate the safety of one, two, or three cycles of imiquimod for the treatment of AK. The AK lesions treated can be in adjacent and nonadjacent areas of the head, torso, and extremities. The total surface area for the AK lesions must be greater than 25 cm2. The secondary objective is to evaluate the effectiveness of treatment with imiquimod in people with large surface areas of AK.

Keratosis

Graceway Pharmaceuticals, LLC551 participantsStarted Jun 2005

Phoenix, Arizona, United States • Encino, California, United States • Los Angeles, California, United States +29 more locations

Phase I Study of U3P1287/01, Including Patients With Advanced Solid Tumors

Open-Label Safety Study to Evaluate Imiquimod Cream, 5% for Large Areas of Actinic Keratosis

Find Trials by Condition in New York

Safety/Efficacy of Everolimus and Neoral® in Adult Cardiac Transplant Patients With Established Allograft Vasculopathy

A Study To Establish The Effects Of PF-04457845 On Sleep In Healthy Volunteers

Safety and Efficacy of PROMETRIUM® Capsules in Induction of Secretory Conversion

A Study Comparing Duloxetine to Other Antidepressants in the Treatment of Severe Depression

Prevention of Atrial Arrhythmia in Patients Without Atrioventricular (AV) Conduction Disease

Efficacy and Safety/Tolerability of Ragweed MATA MPL

Efficacy and Safety/Tolerability of Grass MATA MPL

Validation of an Obstacle Course Used in Patients With Muscle Tightness

Study of LBH589 (Panobinostat) to Treat Malignant Brain Tumors

A Study Comparing Duloxetine and Placebo in the Treatment of Fibromyalgia

Smoking Cessation Program: A Quality Improvement Trial in a Resident-Based Outpatient Clinic

Bioequivalence Study of Levetiracetam Tablets, 750 mg of Dr. Reddy's Under Fed Conditions

SYNTAX Study: TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries

18 Week Study Evaluating Safety and Efficacy of Olmesartan, Amlodipine, and Hydrochlorothiazide, in Type 2 Diabetics

Zinc Supplementation to Reduce Diarrhea Rates in Adults in Western Kenya.

Dose-Finding Study of REN-1654 in Patients With Post-Herpetic Neuralgia

Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.

Safety and Acceptability of SPL7013 Gel (VivaGel™) in Sexually Active Women