Clinical Trials in Nashville

Showing 1941-1960 of 9,711 trials

Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

NCT01734122

The purpose of this study is to determine the changes in quality of life and degree of tremor for patients with essential tremor or Parkinsonian tremor who are treated by stereotactic radiosurgery (SRS). This is a questionnaire-based study. Please see Detailed Description below for more information.

TremorEssential TremorParkinson Disease+2 more

Vanderbilt University Medical Center60 participantsStarted Feb 2013

Nashville, Tennessee, United States

RECRUITING< 1 mile

Periprosthetic Fracture Registry (PPFx)

NCT03378557

This registry supports international data collection and research on PPFx treatments after hip and knee arthroplasty. A registry such as this ultimately aims to provide far-reaching benefits to society including reduced morbidity and mortality, improved patient safety, improved quality of care and medical decision-making, reduced medical spending, and advances in orthopaedic science.

Periprosthetic FracturesPeriprosthetic Fracture Around Prosthetic Joint Implant

AO Innovation Translation Center600 participantsStarted Dec 2018

Columbia, Missouri, United States • Jersey City, New Jersey, United States • Livingston, New Jersey, United States +10 more locations

TERMINATEDPhase 1< 1 mile

Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI)

NCT05231668

SAR439459 is a human anti-Transforming growth factor β (TGFβ) monoclonal antibody. This phase 1 clinical study investigates the safety, tolerability, and activity of a single dose of SAR439459 in adult participants with OI. Participants will receive a single IV dose of SAR439459 with safety, pharmacokinetic (PK), and pharmacodynamic (PD) assessments over 24 weeks. There will be up to 3 dose cohorts. In addition to safety, tolerability, and PK assessments, bone mineral density (BMD) will be evaluated by dual-energy Xray absorptimetry (DXA) scan and a series of blood biomarkers will be monitored to document pharmacodynamic effects of the single dose of SAR439459.

Osteogenesis Imperfecta

Sanofi16 participantsStarted Aug 2022

Los Angeles, California, United States • New Haven, Connecticut, United States • Indianapolis, Indiana, United States +10 more locations

Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

Periprosthetic Fracture Registry (PPFx)

Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI)

Find Trials by Condition in Nashville

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)

A Study of mRNA-1010 Compared With a Licensed Influenza Vaccine in Adults ≥50 Years of Age

Retrospective Study of Suture Tape for Soft Tissue Reconstruction in Patients Suffering From Lateral Ankle Instability

A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy

Study of mRNA Vaccine Formulation Against COVID-19 in Healthy Adults 18 Years of Age and Older

Study to Evaluate the Safety and Efficacy of Pegvaliase in Adolescents (Ages 12-17) With Phenylketonuria

Study of the TearCare System in Dry Eye Disease

Abatacept in Immune Checkpoint Inhibitor Myocarditis

A Study of an Investigational Flu Seasonal/SARS-CoV-2 Combination Vaccine in Adults

Tailored vs. Anatomical Ablation Strategy for Persistent Atrial Fibrillation

A Study of Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04)

A Study to Evaluate the Effect of Deucravacitinib on Quality of Life in Participants With Plaque Psoriasis in a Community Setting

Clinical Utility of Residual Hearing in the Cochlear Implant Ear

A Study of ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Treat Adult Patients Who Have Recently Been Diagnosed With Acute Myeloid Leukemia With a FLT3 Gene Mutation and Who Cannot Receive Standard Chemotherapy

LiveSMART Trial to Prevent Falls in Patients With Cirrhosis

Use of Autologous, Adult Adipose-Derived Stem/Stromal Cells In Chronic Lung Disorders