Clinical Trials in Nashville

Showing 17601-17620 of 20,298 trials

Bendamustine as Second-Line Therapy in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer

NCT00984542

RATIONALE: Drugs used in chemotherapy, such as bendamustine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase II trial is studying how well bendamustine works as second- or third-line therapy in treating patients with relapsed or refractory small cell lung cancer.

Lung Cancer

Vanderbilt-Ingram Cancer Center50 participantsStarted Sep 2009

Elizabethtown, Kentucky, United States • Germantown, Tennessee, United States • Jackson, Tennessee, United States +3 more locations

COMPLETEDPhase 3100 miles

DORADO-AC - Optimized Doses of Darusentan as Compared to an Active Control in Resistant Hypertension

NCT00389779

This is a randomized, double-blind, placebo- and active-controlled study of a new experimental drug called darusentan. Darusentan is not currently approved by the United States Food and Drug Administration (FDA), which means that a doctor cannot prescribe this drug. The purpose of this study is to determine if darusentan is effective in reducing systolic and diastolic hypertension despite treatment with full doses of three or more antihypertensive drugs, including a diuretic. Subjects will be randomized to darusentan (optimized dose), an active comparator, or placebo, administered orally. The treatment period for this trial is 14 weeks.

Hypertension

Gilead Sciences849 participantsStarted Sep 2006

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Huntsville, Alabama, United States +144 more locations

Bendamustine as Second-Line Therapy in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer

DORADO-AC - Optimized Doses of Darusentan as Compared to an Active Control in Resistant Hypertension

Find Trials by Condition in Nashville

An Efficacy and Safety Study of JNJ-26113100 in the Treatment of Adult Atopic Dermatitis

DORADO - Fixed Doses of Darusentan as Compared to Placebo in Resistant Hypertension

Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertension

STA-4783/Paclitaxel or Paclitaxel Alone in Melanoma

Ophthalmologic Safety Study of Pramipexole Immediate Release (IR) Versus Ropinirole in Early Parkinson's Disease (PD) Patients

AMPED Outcomes Registry of Post-ED Pain Management

Study in Advanced Parkinson's Disease Patients With Predictable Motor Fluctuations

Pharmacokinetics of Multiple Ascending Doses of VCH-222 in Subjects With Chronic Hepatitis C Infection

Truvada Versus Truvada Plus Hepatitis B Immunoglobulin (HBIg) in Prevention of Chronic Hepatitis B Recurrence Post Liver Transplant

Mobilization of Stem Cells With AMD3100 (Plerixafor) in Multiple Myeloma Patients

Adult Double Cord Blood Transplant Study

A Comparison of the dermaPACE® (Pulsed Acoustic Cellular Expression) Device in Conjunction With Standard of Care Versus Standard of Care Alone in the Treatment of Diabetic Foot Ulcers

Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Patients With Cystic Fibrosis and Chronic Burkholderia Species Infection

Mobilization of Stem Cells With AMD3100 (Plerixafor) and G-CSF in Non-Hodgkin's Lymphoma and Multiple Myeloma Patients

Long-term Effects of Highly Active Anti-Retroviral Therapy on HIV-Infected Children

Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACU-4429 in Subjects With Geographic Atrophy

To Compare the Pharmacokinetics of a Single Oral Dose of TC-5214 in Subjects With Renal Impairment and With Subjects With Normal Renal Function

Fludarabine (Fludara®) Plus Alemtuzumab (CAMPATH®, MabCampath®) vs Fludarabine Alone in B-Cell Chronic Lymphocytic Leukemia (B-CLL) Patients