Clinical Trials in Nashville

Showing 14401-14420 of 20,298 trials

Open-Label Study to Assess the Safety/Tolerability in Patients With Solid Tumors

NCT00820560

To establish the maximum tolerated dose (MTD) of INCB007839 given as multiple doses for 28 days and to determine if a higher MTD can be established when INCB007839 is administered in combination with prophylactic anticoagulation and with a 2 and a half day (5 doses) treatment interruption every two weeks.

Solid Tumors and Hematologic Malignancy

Incyte Corporation41 participantsStarted Jan 2005

Aurora, Colorado, United States • Baltimore, Maryland, United States • Philadelphia, Pennsylvania, United States +1 more locations

COMPLETEDPhase 3< 1 mile

Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma

NCT01480479

This 2-arm, randomized, phase III study will investigate the efficacy and safety of the addition of rindopepimut (an experimental cancer vaccine that may act to promote anti-cancer effects in patients who have tumors that express the EGFRvIII protein) to the current standard of care (temozolomide) in patients with recently diagnosed glioblastoma, a type of brain cancer. All patients will be administered temozolomide, the standard treatment for glioblastoma. Half the patients will be randomly assigned to receive rindopepimut and half the patients will be randomly assigned to receive a control called keyhole limpet hemocyanin. Patients will be treated in a blinded fashion (neither the patient or the doctor will know which arm of the study the patient is on). Patients will be treated until disease progression or intolerance to therapy and all patients will be followed for survival.

GlioblastomaSmall Cell GlioblastomaGiant Cell Glioblastoma+2 more

Celldex Therapeutics745 participantsStarted Nov 2011

Birmingham, Alabama, United States • Mobile, Alabama, United States • Phoenix, Arizona, United States +220 more locations

Open-Label Study to Assess the Safety/Tolerability in Patients With Solid Tumors

Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma

Find Trials by Condition in Nashville

Cognitive Rehabilitation:ACTION Training for Soldiers With Executive Dysfunction

The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor

A Study of the Trabecular Micro-bypass Stent in Combination With Cataract Surgery in Subjects With Open Angle Glaucoma

Study to Evaluate the Efficacy and Safety of P-3058 Nail Solution in the Treatment of Onychomycosis

Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT)

Dolutegravir Compared to Darunavir/Ritonavir , Each in Combination With Dual Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in ART-naive Subjects

EGEN-001 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

An Open Label Demonstration Project and Phase II Safety Study of Pre-Exposure Prophylaxis

Phase II Study of the Safety and Efficacy of the Relay Thoracic Stent-Graft

Alendronate to Prevent Loss of Bronchoprotection in Asthma

Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS)

Study to Assess the Safety and Tolerability of Intravenous Carbamazepine in Adults With Epilepsy

3-year Follow-up Study to Assess the Viral Activity in Hepatitis C Patients Who Failed Feeder DEB025/Alisporivir Study

A Study in Type 2 Diabetics of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

A Dose Ranging Trial of GSK1349572 and 2 NRTI in HIV-1 Infected, Therapy Naive Subjects

The FIRSTT: Comparing MRgFUS(MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization)for Uterine Fibroids.

Multi-site Validation and Application of a Consensus DSC-MRI Protocol

A Soft Silicone Wound Contact Layer Containing Silver in the Treatment of Skin Grafts in Surgical Burn Patients.