Clinical Trials in Nashville

Showing 13181-13200 of 19,451 trials

A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid Tumors

NCT01708161

This was a multi-center, open-label, phase Ib/II study. The aim of the phase Ib part was to estimate the MTD(s) and/or identify the recommended phase II dose(s) (RP2Ds) for the combination of BYL719 and AMG 479 (ganitumab), followed by the phase II part to assess the clinical efficacy and to further assess the safety of the combination in selected patient populations. Patients were to be treated until progression of disease, unacceptable toxicity develops, or withdrawal of informed consent, whichever occurred first. All patients were to be followed up. At a minimum, patients must have completed the safety follow-up assessments 30 days after the last dose of the study treatment.

PIK3CA Mutated Advanced Solid TumorsPIK3CA Amplified Advanced Solid Tumors

Novartis Pharmaceuticals47 participantsStarted Nov 2012

Los Angeles, California, United States • Boston, Massachusetts, United States • New York, New York, United States +7 more locations

TERMINATEDPhase 1< 1 mile

Dose-Escalation Study of ABBV-838, an Antibody Drug Conjugate, in Subjects With Relapsed and Refractory Multiple Myeloma

NCT02462525

This is a Phase 1/1b, open-label, dose-escalation study designed to evaluate the safety, pharmacokinetics, and to determine the recommended Phase 2 dose of ABBV-838 in subjects with relapsed and refractory multiple myeloma.

Multiple Myeloma

AbbVie74 participantsStarted May 2015

Chicago, Illinois, United States • Ann Arbor, Michigan, United States • St Louis, Missouri, United States +16 more locations

A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid Tumors

Dose-Escalation Study of ABBV-838, an Antibody Drug Conjugate, in Subjects With Relapsed and Refractory Multiple Myeloma

Find Trials by Condition in Nashville

Preventing Hypoxemia With Manual Ventilation During Endotracheal Intubation (PreVent) Trial

A Phase 3 Study Comparing the Effects of Intravenous Epoetin Hospira and Epoetin Alfa [Epogen] (Amgen) in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin

Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor

Study to Evaluate the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Quadrivalent Influenza Vaccine (GSK2282512A) Compared to Fluzone® Quadrivalent in Children 6 to 35 Months of Age

Cognition in the Study of Tamoxifen and Raloxifene

Pomaglumetad Effects on Glutamate Biomarkers

Effect of Intravenous (IV) Vedolizumab on Mucosal Healing in Crohn's Disease

Physical and Cognitive Function - Look AHEAD Ancillary Study

A Phase 2 Multicenter Randomized Clinical Trial of CNTF for MacTel

Tivantinib in Treating Patients With Metastatic Prostate Cancer

An Assessment of the Glider Balloon in Complex Lesions

Chocolate Balloon Angioplasty Registry

Surefire Precision Infusion System Registry

OPTIMA: Efficacy of Optimized Re-treatment and Step-up Therapy With Omalizumab in Chronic Spontaneous Urticaria (CSU) Patients

Natural History Study to Characterise the Course of Disease Progression in Participants With Mucopolysaccharidosis Type IIIB

Study of Room Air Versus 60% Oxygen for Resuscitation of Premature Infants

A Study Comparing Two Treatments for Infants With Hydrocephalus

Open Label Extension Study With Gefitinib (IRESSA™) for Completing Trial Patients Who May Benefit From Further Treatment