Clinical Trials in Nashville

Showing 12781-12800 of 17,403 trials

Serotonin 1A Agonists and Cognition in Schizophrenia

NCT00178971

Examines cognitive functioning in patients with schizophrenia or schizoaffective disorder who have been treated with antipsychotic medications. Patients will be assigned to take active medication (Buspar)or placebo along with their prescribed antipsychotic medication for six weeks. Patients' memory and problem-solving ability will be tested before and after medication.

SchizophreniaSchizoaffective Disorder

Northwestern University60 participantsStarted Jan 2003

Nashville, Tennessee, United States

TERMINATEDPhase 1< 1 mile

How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units

NCT00826553

The purpose of this study is to study the effect of two standard of care sedative medications on sleep stages and total sleep time. The investigators hypothesize that the α2 agonist, dexmedetomidine, will improve sleep quality by increasing N2 and N3 sleep as well as total sleep time when compared to GABA agonists.

DeliriumRespiratory Failure

Vanderbilt University Medical Center6 participantsStarted Jan 2009

Nashville, Tennessee, United States

COMPLETEDPhase 2< 1 mile

Citrulline in Severe Sepsis

NCT01474863

This is a randomized, double-blind, placebo-controlled, phase 2 study to evaluate biochemical, clinical, and safety effects of 2 doses of intravenous L-citrulline compared to placebo in patients with severe sepsis at risk for or with acute lung injury. The hypothesis is that intravenous L-citrulline will decreased the development or progression of acute lung injury in patients with severe sepsis compared to placebo.

Severe SepsisAcute Lung Injury

Vanderbilt University72 participantsStarted Aug 2012

Nashville, Tennessee, United States

Serotonin 1A Agonists and Cognition in Schizophrenia

How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units

Citrulline in Severe Sepsis

Find Trials by Condition in Nashville

A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)

Bisphosphonate Treatment of Osteogenesis Imperfecta

A Multicenter, Open-label, Phase 1b Study of Carfilzomib, Cyclophosphamide and Dexamethasone in Newly Diagnosed Multiple Myeloma Subjects

A Phase 1b Study to Assess the Safety and Anti-inflammatory Effects of Two Different Doses of SRT2104 in Patients With Ulcerative Colitis

A Phase 2, Multicenter, Open-label Study of MEDI-551 in Adults With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time

Sexual Functioning Study With Antidepressants

Lethargic Depression Study

Monitoring Disease Activity Using Video Capsule Endoscopy (VCE) in Crohn's Disease (CD) Subjects

A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease Therapy

A Three-part Study of Eltrombopag in Thrombocytopenic Subjects With Myelodysplastic Syndromes or Acute Myeloid Leukemia

Dose Ranging of GSK2336805 in Combination Therapy

Covered Metallic Stents for First-Line Treatment of Benign Bile Duct Strictures

Efficacy of Prednisone In the Treatment of Ocular Myasthenia

Rollover Protocol Continued Access to Emtricitabine/Tenofovir Disoproxil Fumarate for Adults in United States

A Long Term Safety Study of Mavrilimumab in Adult Subjects With Rheumatoid Arthritis

BOTOX® Efficacy and Safety in the Treatment of Knee Osteoarthritis