Clinical Trials in Nashville

Showing 11461-11480 of 17,403 trials

Mental Ability Challenge Study in Adults With and Without HIV

NCT03244488

It is estimated that by 2016, nearly 50% of HIV-positive individuals in the US will be aged 50 or older, and up to 60% of those will experience some degree of cognitive impairment as they age. The purpose of this study is to evaluate the contribution of the neuronal cholinergic receptor system to the cognitive impairments seen in adults aging with chronic HIV Infection. By using anti-cholinergic challenge drugs to reversibly "stress" cognitive functioning, the investigators hope to understand whether the presence of the HIV virus in the brain impairs the neural system necessary for normal cognition, more than would be expected from normal cognitive aging.

HIV-1-infectionAging, PrematureCognitive Impairment+2 more

Vanderbilt University Medical Center22 participantsStarted Dec 2015

Nashville, Tennessee, United States

COMPLETEDPhase 2/3< 1 mile

Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)

NCT01881230

The purpose of this study is to compare the safety and efficacy of nab-paclitaxel in combination with either gemcitabine or carboplatin to the combination of gemcitabine and carboplatin as first line treatment in female subjects with triple negative metastatic breast cancer (TNMBC) or metastatic triple negative breast cancer.

Breast TumorBreast CancerCancer of the Breast+8 more

Celgene191 participantsStarted Sep 2013

Chandler, Arizona, United States • Glendale, Arizona, United States • Scottsdale, Arizona, United States +137 more locations

Mental Ability Challenge Study in Adults With and Without HIV

Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)

Find Trials by Condition in Nashville

Brain Penetrance of 2-HOBA in Humans

Safety and Efficacy of Automatic Testing Feature in New ICDs and CRT-Ds

Aortic Valve Replacement With Trifecta(TM)

GSK1120212 Rollover Study

Detect Fluid Early From Intra-thoracic Impedance Monitoring

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound

Efficacy and Safety Evaluation of AN2690 Topical Solution to Treat Onychomycosis of the Toenail

Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD

Thyroid Therapy for Mild Thyroid Deficiency in Pregnancy

Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)

Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS)

Veterans Individual Placement and Support Towards Advancing Recovery

eHealth Partnered Evaluation Initiative

CONcomitant eValuation of Epicor Left atRial Therapy for AF

NuShield/Affinity for the Treatment of Neuropathic Diabetic Foot Ulcers

A Study to Evaluate the Safety of Aceneuramic Acid Extended Release (Ace-ER; UX001) Tablets in Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy (GNEM) (Also Known as Hereditary Inclusion Body Myopathy [HIBM]) Patients With Severe Ambulatory Impairment

FREEDOM - A Frequent Optimization Study Using the QuickOpt Method

Heart Outcomes Prevention and Evaluation 4