Clinical Trials in Nashville

Showing 9341-9360 of 20,298 trials

A Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic Malignancies

NCT03241173

The purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01949 when given in combination with immune therapies in participants with advanced or metastatic malignancies.

Advanced Malignancies

Incyte Biosciences International Sàrl52 participantsStarted Oct 2017

Birmingham, Alabama, United States • Scottsdale, Arizona, United States • Los Angeles, California, United States +12 more locations

TERMINATEDPhase 1< 1 mile

Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies.

NCT03218683

This study is a multicenter, open-label, nonrandomized, sequential group, dose-escalation study to assess safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of ascending doses of AZD5991 in subjects with relapsed or refractory hematologic malignancies Part 1 of the study is monotherapy dose escalation. Closed November 2020 Part 2 of the study is monotherapy expansion groups for relapsed/refractory chronic lymphocytic leukaemia (CLL), AML/ myelodysplastic syndromes (MDS), and multiple myeloma (MM). Closed November 2020 Part 3 is a sequential, dose-escalation study of the combination of AZD5991 and venetoclax in subjects with relapsed/refractory AML

Relapsed or Refractory Acute Myeloid Leukemia (AML)

AstraZeneca70 participantsStarted Aug 2017

Orange, California, United States • Aurora, Colorado, United States • Atlanta, Georgia, United States +7 more locations

A Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic Malignancies

Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies.

Find Trials by Condition in Nashville

A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC

Fibromyalgia Outcome Research Trial Evaluating Synergistic Suppression of HSV-1

A Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma

Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry

Study of Romosozumab (AMG 785) in Tibial Diaphyseal Fractures Status Post Intramedullary Nailing

An Efficacy Study of MORAb-009 (Amatuximab) in Subjects With Pleural Mesothelioma

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular Degeneration

Long Term Follow Up Study to COMP 001 And COMP 003 Trials (P-TRD LTFU)

Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

Comparison of VT Ablation Outcomes Using Remote MAGNETIC Navigation Versus Manual Approach in a Low LVEF Population

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a))

Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma

A Study of the Safety of INCB054707 in Participants With Hidradenitis Suppurativa

Natural History Study in Huntington Disease Gene Expansion Carriers (HDGECs) - SHIELD HD

Long-Term Retention of Gadolinium in Bone