Clinical Trials in Nashville

Showing 7301-7320 of 15,379 trials

PDE5 Inhibition for Obesity-Related Cardiometabolic Dysfunction

NCT02819440

Obesity and its adverse cardiometabolic consequences are major public health problems. Several features of obesity contribute to the associated cardiovascular risk and are potential targets for intervention. These include insulin resistance and beta cell dysfunction, reduced metabolic rate, and impaired aerobic capacity.The purpose of this study is to examine if the phosphodiesterase type 5A inhibitor tadalafil improves cardiometabolic health in individuals who are obese and insulin resistant.

HealthyObese

Vanderbilt University Medical Center141 participantsStarted Jul 2016

Nashville, Tennessee, United States

COMPLETEDPhase 2< 1 mile

Safety and Immunogenicity of the RSV-F Vaccine in Older Adults Previously Treated With the Same Vaccine or Placebo in the Prior Year.

NCT02593071

This study will enroll subjects who received the RSV F vaccine or placebo in the earlier study (RSV-E-201, Year 1) and re-randomize them to receive either vaccine or placebo in a second season. This design will permit evaluation of the safety and immunogenicity of revaccination in a second RSV season, and the safety and immunogenicity of revaccination over two years.

Respiratory Syncytial Virus (RSV)

Novavax1,330 participantsStarted Oct 2015

Redding, California, United States • Stockbridge, Georgia, United States • Lenexa, Kansas, United States +7 more locations

PDE5 Inhibition for Obesity-Related Cardiometabolic Dysfunction

Safety and Immunogenicity of the RSV-F Vaccine in Older Adults Previously Treated With the Same Vaccine or Placebo in the Prior Year.

Find Trials by Condition in Nashville

Safety of Tinted Soft Scleral Eye Shields When IPL is Applied on Eyelids

Efficacy and Safety of Vedolizumab Subcutaneously (SC) as Maintenance Therapy in Ulcerative Colitis

Combination Chemotherapy With or Without Hypofractionated Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer

Adherence With Continuous-dose Oral Contraceptive: Evaluation of Self-Selection and Use

Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Situ

Improving Women's and Children's Health Via Biobanking and Electronic Registry

A Study to Evaluate Efficacy and Safety of AG-348 in Not Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)

Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer

PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies

Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults With Chronic Hepatitis B

Long-Term Treatment and Follow up of Subjects Completing 24 Months of Treatment With Tesevatinib on Study KD019-101

An Investigational Immunotherapy Study of BMS-986299 Alone and in Combination With Nivolumab and Ipilimumab in Participants With Solid Cancers That Have Spread or Cannot be Removed

RSV F Vaccine Maternal Immunization Study in Healthy Third-trimester Pregnant Women.

Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction

The TOGETHER Project - Liver

First in Human Testing of Dose-escalation of SAR440234 in Patients With Acute Myeloid Leukemia, Acute Lymphoid Leukemia and Myelodysplastic Syndrome

Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current Smokers

Ahmed Glaucoma Valve Surgery With Mitomycin-C