Clinical Trials in Nashville

Showing 3261-3280 of 20,298 trials

A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer

NCT04294160

A phase Ib, open-label platform study of select drug combinations chosen in order to characterize safety and tolerability of each treatment arm tested and to identify recommended doses and regimens for future studies.

BRAF V600 Colorectal Cancer

Novartis Pharmaceuticals122 participantsStarted Jul 2020

Los Angeles, California, United States • Boston, Massachusetts, United States • Nashville, Tennessee, United States +15 more locations

RECRUITINGPhase 2< 1 mile

A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV

NCT06812494

HVTN 206/HPTN 114 is a randomized, double blind, controlled, phase 2 clinical trial to evaluate the safety, tolerability, pharmacokinetics, and neutralization of VRC07-523LS, PGT121.414.LS, and PGDM1400LS broadly neutralizing monoclonal antibodies given intravenously in adult participants without HIV. The hypothesis of the study is that the combination of VRC07-523LS and PGT121.414.LS and PGDM1400LS antibodies when administered via the intravenous (IV) route will be safe and tolerable in adult participants without HIV. The study aims to enroll 200 participants across multiple sites with an estimated total duration of participation of eighteen (18) months.

HIV

National Institute of Allergy and Infectious Diseases (NIAID)200 participantsStarted Mar 2025

Birmingham, Alabama, United States • San Francisco, California, United States • Decatur, Georgia, United States +18 more locations

A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer

A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV

Find Trials by Condition in Nashville

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

Safety and Efficacy of Turoctocog Alfa Pegol (N8-GP) in Previously Untreated Patients With Haemophilia A

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

Stroke Thrombectomy and Aneurysm Registry

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

Study of Pregnancy And Neonatal Health (SPAN)

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL

An Immuno-therapy Study to Evaluate the Effectiveness, Safety and Tolerability of Nivolumab or Nivolumab in Combination With Other Agents in Patients With Advanced Liver Cancer

SpineTRACK Registry - Spinal Outcomes Registry

Osteocel® Plus in Anterior Lumbar Interbody Fusion (ALIF)

Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

A Prospective Non-concurrent Controlled Evaluation of Open and MAS® PLIF

Clinical and Molecular Studies in Families With Inherited Eye Disease

A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation

A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors