Clinical Trials in Nashville

Showing 3081-3100 of 15,379 trials

Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

NCT07142252

This Phase 2 study is a 2-arm, multi-center, double-masked, placebo-controlled, 2:1 randomized sequential trial design in new onset T1D participants (within 100 days of diagnosis). Participants will be administered rezpegaldesleukin/placebo once every 14 days over 26 weeks with an additional 6-month follow-up period.

Type 1 Diabetes Mellitus

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)66 participantsStarted Nov 2025

Nashville, Tennessee, United States

RECRUITINGNA< 1 mile

Home-Based Cardiac Rehabilitation for Patients With Heart Failure

NCT06479876

The vast majority of individuals with heart failure do not participate in center based cardiac rehabilitation (CBCR). While steps to increase utilization of CBCR are important, many individuals will still not participate for a variety of reasons. This pilot randomized controlled trial is evaluating a home-based cardiac rehabilitation (HBCR) intervention delivered using a custom app and digital tools in patients with heart failure. After a brief roll-in period, participants are randomized to one of two groups: (1) control or (2) HBCR mobile health intervention. The intervention targets key health behaviors and includes traditional cardiac rehabilitation components. The study will assess the effect of the intervention on physical activity, quality of life, clinical events, and other outcomes.

Heart Failure With Preserved Ejection FractionHeart Failure With Reduced Ejection FractionCardiovascular Diseases

Vanderbilt University Medical Center100 participantsStarted Aug 2024

Nashville, Tennessee, United States

Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

Home-Based Cardiac Rehabilitation for Patients With Heart Failure

Find Trials by Condition in Nashville

Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

Phase 2a Study of VX-147 in Adults With APOL1-mediated Focal Segmental Glomerulosclerosis

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis

A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery

A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium

Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

Beta-Agonist Versus OnabotulinumtoxinA Trial for Urgency Urinary Incontinence

Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion

A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

An Observational Registry of Abatacept in Patients With Juvenile Idiopathic Arthritis

Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis

Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants

A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations

Neoadjuvant Durvalumab and Tremelimumab With and Without Chemotherapy for Mesothelioma

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

A Research Study to Evaluate the Safety of NNC4004-0002 When Given to Participants With Asymptomatic Hyperuricemia

A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF)