Clinical Trials in Nashville

Showing 2221-2240 of 9,711 trials

A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors

NCT04257110

This is an open-label, first-in-human (FIH), phase 1 dose-escalation and cohort expansion study of BB-1701 in subjects with locally advanced/metastatic HER2 expressing solid tumors. The study consists of 2 parts: dose-escalation (Part 1) and cohort expansion (Part 2). Part 1 consists of dose escalation cohorts for determining the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D). Part 2 consists of expansion cohorts, including but not limited to breast cancer, gastric/gastroesophageal junction cancer, bladder cancer and colon cancer, for exploring 1 or more RP2Ds or schedules for expanding/deepening the information/knowledge about clinical safety, clinical pharmacokinetics and anti-tumor activity.

Locally Advanced/Metastatic HER2 Positive Solid Tumors

Bliss Biopharmaceutical (Hangzhou) Co., Ltd117 participantsStarted Jul 2020

San Francisco, California, United States • Nashville, Tennessee, United States • Fairfax, Virginia, United States +9 more locations

COMPLETEDPhase 3< 1 mile

Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis

NCT04028492

To investigate the safety and efficacy of tradipitant versus placebo in relieving nausea and other symptoms of gastroparesis.

Idiopathic GastroparesisDiabetic GastroparesisGastroparesis

Vanda Pharmaceuticals992 participantsStarted Aug 2019

Birmingham, Alabama, United States • Peoria, Arizona, United States • Little Rock, Arkansas, United States +33 more locations

A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors

Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis

Find Trials by Condition in Nashville

A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

PRECIDENTD Engagement Methods for Sites

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (TENAYA)

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

A Study of LY2784544 in Participants With Myeloproliferative Neoplasms

Wavefront-guided LASIK for Monovision Treatment of Myopic Subjects With Presbyopia

Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (MCL)

A Study to Assess the Safety and Immune Response of a Vaccine Against Influenza in Healthy Younger and Older Adults

Study of NGM282 in Patients With Nonalcoholic Steatohepatitis (NASH)

Study Evaluating the Safety and Efficacy of AR-15512 (COMET-3)

A-LiNK: Improving Outcomes in Autoimmune Liver Disease

A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease

Virtual Care to Improve Heart Failure Outcomes (VITAL-HF)

A Post-Market Study for Long-Term Effectiveness and Safety of the NTX100 for RLS

Rhythm Express Wearable System vs. Simultaneous Polysomnography for the Diagnosis of Obstructive Sleep Apnea in Adults With Suspected or Observed Atrial Fibrillation

Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp

Non-surgical Spinal Decompression Therapy and Outcomes