Clinical Trials in Nashville

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Safety and Immunogenicity Study of LC16m8, a Modified Smallpox Vaccine, in Healthy, Previously Unvaccinated Volunteers

NCT00103584

This is a Phase I/II study evaluating the safety and immunogenicity of LC16m8, a modified vaccinia vaccine. After consent and thorough screening (including safety labs, EKG, and medical history), healthy, previously unvaccinated volunteers between the ages of 18-34 will receive a single vaccination of either LC16m8 or the current US-licensed smallpox vaccine, Dryvax. Volunteers will be blindly randomized to a treatment group in a 4:1 ratio (4 LC16m8 to 1 Dryvax recipient). Follow-up clinical evaluations, laboratory testing, EKGs and cardiac assessments will be done at regularly scheduled follow-up visits for 1 year after vaccination.

Smallpox

VaxGen150 participantsStarted Oct 2004

Stanford, California, United States • Lexington, Kentucky, United States • St Louis, Missouri, United States +1 more locations

COMPLETEDPhase 2< 1 mile

To Evaluate the Long-Term Safety of Pregabalin in Refractory Partial Epilepsy.

NCT00141414

To evaluate the long-term safety of pregabalin in refractory partial epilepsy.

Epilepsy, Partial

Pfizer82 participantsStarted Nov 1997

Little Rock, Arkansas, United States • Los Angeles, California, United States • Stanford, California, United States +22 more locations

Safety and Immunogenicity Study of LC16m8, a Modified Smallpox Vaccine, in Healthy, Previously Unvaccinated Volunteers

To Evaluate the Long-Term Safety of Pregabalin in Refractory Partial Epilepsy.

Find Trials by Condition in Nashville

Study Evaluating MST-997 in Advanced Malignant Solid Tumors

A Phase 2, Randomized, Open-Label Study Of Single Agent CI-1033 In Patients With Advanced Non-Small Cell Lung Cancer

Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure.

3-D Laser Imaging to Analyze Neck Movement

Study Evaluating the Safety & Efficacy of DVS-223 SR for Relief of Vasomotor Symptoms Associated With Menopause

Evaluation of Argatroban Injection in Pediatric Patients Requiring Anticoagulant Alternatives to Heparin

A Study to Evaluate the Single-Agent Lenalidomide in Subjects With Recurrent Non-Small-Cell Lung Cancer

Study of Nitazoxanide in the Treatment of Clostridium Difficile Colitis

Autologous T Cell Immunotherapy for Chronic Lymphocytic Leukemia (CLL) Patients

Study for Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)

T Cell Immunotherapy for Multiple Myeloma Patients Undergoing a Bone Marrow Transplant

APC-231 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) in Pediatric Patients With Strep Throat

Pemetrexed Plus Gemcitabine for Patients With Locally Advanced or Metastatic NSCLC Who Have Not Had Previous Chemotherapy.

SP01A: The Study of an Oral Entry Inhibitor in Treatment-Experienced HIV Patients

Safety and Immunogenicity of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non-Small Cell Lung Cancer

Study Of An Oral Tyrosine Kinase Inhibitor Of VEGFR-2 To Treat Small-Volume Ovarian, Peritoneal, Fallopian Tube Cancer

Chemotherapy for Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Bipolar Depression Study: Bipolar Depression Assessment Study on Treatment Response