Clinical Trials in Minneapolis

Showing 2841-2860 of 14,456 trials

Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease

NCT06405334

Balance problems and falls are among the most common complaints in Veterans with Parkinson's Disease (PD), but there are no effective treatments and the ability to measure balance and falls remains quite poor. This study uses wearable sensors to measure balance and uses deep brain stimulation electrodes to measure electric signals from the brain in Veterans with PD. The investigators hope to use this data to better understand the brain pathways underlying balance problems in PD so that new treatments to improve balance and reduce falls in Veterans with PD can be designed.

Parkinson's Disease

VA Office of Research and Development100 participantsStarted Nov 2024

Minneapolis, Minnesota, United States

Active Not RecruitingNA< 1 mile

Neuspera's Implantable Sacral Nerve Stimulation System in Patients With Symptoms of Urinary Urgency Incontinence (UUI)

NCT04232696

Prospective, multi-center, single-arm, seamless phase-pivotal study conducted in participants diagnosed with UUI who have failed or could not tolerate more conservative treatment. The trial will be conducted in two phases. Objective of Phase I: To assess the utilization of the system during the Sacral Nerve Stimulation (SNS) trial period and to help inform the length of hours of daily stimulation to be used in Phase II of the trial. Objective of Phase II: To assess the safety and efficacy of the Neuspera SNS System at 6-months for the primary efficacy endpoint and at 12 months for secondary safety and efficacy endpoints.

Urinary Urgency Incontinence

Neuspera Medical, Inc.331 participantsStarted Dec 2019

Encinitas, California, United States • Los Angeles, California, United States • San Diego, California, United States +31 more locations

Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease

Neuspera's Implantable Sacral Nerve Stimulation System in Patients With Symptoms of Urinary Urgency Incontinence (UUI)

Find Trials by Condition in Minneapolis

Combining a Smartphone App With Medications to Manage Heavy Drinking

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Adolescent Stargardt Disease

CMVIG Prophylaxis in Belatacept Conversion Kidney Transplant Recipients

Study to Compare the Safety and Efficacy of IDP-126 Gel to Epiduo® Forte Gel and Vehicle Gel

Post-Market Study to Assess iTind Safety in Comparison to UroLift

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1

A Study to Describe the Characteristics, Health Care Interventions and Outcomes of Patients With Major Bleedings in the Presence of Factor Xa Inhibitor Treatment

Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)

MDR - Comprehensive Primary/Micro Stem & Versa-Dial Ti Humeral Head

To Evaluate Safety and Tolerability of the Fixed- Dose Combination of Obeticholic Acid and Bezafibrate

A Modular Phase 1/2 Study With CT7439 in Participants With Solid Malignancies

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST

Study of Disease Progression in Adults With Inherited Forms of Spastic Paraplegia