Clinical Trials in Minneapolis

Showing 2041-2060 of 6,957 trials

Backtracking Leukemia-Typical Somatic Mutations in Cord Blood

NCT05014165

A comprehensive mechanistic and epidemiological study to obtain banked cord blood samples from consecutive childhood leukemia patients enrolled in the COG Project:EveryChild (APEC14B1) study. Will attempt to backtrack the initiating genomic alteration identified in the matched diagnostic leukemia sample and molecularly characterize pre-leukemic cells. The ultimate goal of this research is to pinpoint the cell of origin of leukemogenic alterations formed in utero, elucidating the etiology of these initiating mutations (as opposed to frank leukemia), and devising a test for circulating pre-leukemia that can be applied on a population-wide basis.

Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia

Children's Oncology Group300 participantsStarted Aug 2021

Minneapolis, Minnesota, United States

COMPLETEDPhase 1< 1 mile

A Study of JNJ-80038114 in Participants With Advanced Stage Prostate Cancer

NCT05441501

The purpose of this study is to determine recommended phase 2 dose(s) (RP2Ds) of JNJ-80038114 in Part 1 (dose escalation) and to determine the safety at the RP2D(s) in Part 2 (dose expansion).

Prostatic Neoplasms

Janssen Research & Development, LLC39 participantsStarted Nov 2022

Minneapolis, Minnesota, United States • Philadelphia, Pennsylvania, United States • Nashville, Tennessee, United States +3 more locations

COMPLETEDPhase 2< 1 mile

Phase 2 Trial to Evaluate Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma

NCT04417530

The primary objective is to determine the safety, tolerability, and preliminary efficacy of belzupacap sarotalocan for the treatment of primary indeterminate lesions and small choroidal melanoma (IL/CM).

Uveal MelanomaOcular MelanomaChoroidal Melanoma

Aura Biosciences22 participantsStarted Aug 2020

Tucson, Arizona, United States • Los Angeles, California, United States • Palo Alto, California, United States +19 more locations

Backtracking Leukemia-Typical Somatic Mutations in Cord Blood

A Study of JNJ-80038114 in Participants With Advanced Stage Prostate Cancer

Phase 2 Trial to Evaluate Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma

Find Trials by Condition in Minneapolis

NAP in Combination With Docetaxel Following Obinutuzumab Pretreatment in Subjects With Checkpoint Inhibitor Pretreated Advanced or Metastatic NSCLC

Safety and Effectiveness Study of Endovascular Abdominal Aortic Aneurysm Repair Using the Nellix® System

LEO 90100 Compared With Calcipotriol Plus Betamethasone Dipropionate Ointment, LEO 90100 Vehicle and Ointment Vehicle in Subjects With Psoriasis Vulgaris

Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome

TAEK-VAC-HerBy Vaccine for Brachyury and HER2 Expressing Cancer

Study of Lanreotide Autogel in Non-functioning Entero-pancreatic Endocrine Tumours

EPI-7386 in Combination with Enzalutamide Compared with Enzalutamide Alone in Subjects with MCRPC

MGD019 DART® Protein in Unresectable/Metastatic Cancer

Safety and Efficacy of Oral GKT137831 in Patient With Type 2 Diabetes and Albuminuria

Screening Protocol for Tumor Antigen Expression Profiling and HLA Typing for Eligibility Determination

A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer

Development of a Health-Related Symptom Index for Participants With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions

A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes.

XB2001 in Combination With ONIVYDE + 5-FU/LV (+Folinic Acid) in Advanced Pancreatic Cancer

A Study Evaluating ANV600 Single Agent or in Combination with Pembrolizumab in Participants with Advanced Solid Tumors (EXPAND-1)

Effectiveness and Safety of Restylane Lyft Lidocaine for Jawline Definition

An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice