Clinical Trials in Miami

Showing 701-720 of 5,521 trials

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

NCT05395481

The main purpose of this study is to evaluate the safety and tolerability of the study drug LY3849891 in participants with metabolic dysfunction-associated steatotic liver disease (MASLD) who have the patatin-like phospholipase domain-containing protein 3 (PNPLA3) I148M genotype. Blood tests and magnetic resonance imaging of the liver will be performed to determine the effects of LY3849891 on MASLD and assessment of resolution of liver fibroinflammation. Blood tests will also determine how long it takes the body to eliminate LY3849891. This is a 2-part study and may last up to 32 weeks for each participant and may include 12 visits in parts A and B.

Metabolic Dysfunction-Associated Steatohepatitis (MASH)Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)

Eli Lilly and Company176 participantsStarted Jun 2022

Chandler, Arizona, United States • Orange, California, United States • Rialto, California, United States +13 more locations

ACTIVE_NOT_RECRUITINGPHASE1< 1 mile

Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia

NCT05001828

Pegylated arginine deiminase (ADI-PEG 20) will be combined with venetoclax and azacitidine for treatment of subjects with previously treated or untreated with high risk factor acute myeloid leukemia (AML). Venetoclax and azacitidine are front-line therapy for such patients, and ADI-PEG 20 will be added to this regimen in a phase IA/B study.

Acute Myeloid Leukemia, Adult

Polaris Group38 participantsStarted Apr 2022

Miami, Florida, United States • Charlotte, North Carolina, United States • Houston, Texas, United States

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia

Find Trials by Condition in Miami

Prospective Evaluation of Open Irrigated Ablation Catheters With High Resolution Mapping to Treat Paroxysmal Atrial Fibrillation

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

A Study to Learn About a Vaccine Against E Coli in Healthy Adults

Caris Biorepository Research Protocol

Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Equity in Modifying Plaque Of WomEn With UndeRtreated Calcified Coronary Artery Disease

Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial

A Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Participants With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy

A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity

The PediQUEST Response to Pain Of Children With Neurologic Disability Pilot Randomized Controlled Trial

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

EXoPERT EMERALD Clinical Study

Interventional Study of Vosoritide for the Treatment of Children With Hypochondroplasia

A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer

5-Year Global Study on MAST™ Minimally Invasive Fusion Procedures to Treat Degenerative Lumbar Spine (MASTERS-D2)