Clinical Trials in Miami

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Novel Approach to Stimulant Induced Weight Suppression and Its Impact on Growth

NCT01109849

Previous NIH funded Attention Deficit Hyperactivity Disorder (ADHD) trials in children found that daily stimulant therapy produced sustained growth deficits. However, no federally funded studies have examined the growth suppression associated with modern once a day stimulant medications. Therefore, this study will precisely estimate the risks of stimulant induced growth suppression (SIGS), examine the underlying mechanisms and develop treatments for it. While drug holidays and caloric supplementation are two common treatments for SIGS, there has been little systematic investigation of either. It is unknown if they are effective or feasible. Therefore, using a randomized adaptive design, we will evaluate the efficacy and feasibility of these two practices vs. routine monitoring of growth in 180 prepubertal children with ADHD. An additional 50 subjects will be treated solely with behavioral therapies to evaluate for growth abnormalities associated with ADHD. The study will assess will the risk of SIGS with ER stimulants and the underlying mechanisms while providing evidenced-based treatments for its management.

ADHDGrowth

Florida International University230 participantsStarted Nov 2010

Miami, Florida, United States

COMPLETEDPhase 2< 1 mile

Treatment Of Patients With Social Anxiety Disorder

NCT00397722

GW876008 is a drug which may change mans reaction to stress, by decreasing the fear, physical and behavior symptoms that people with SocAD experience in social situations.

Social Phobia

GlaxoSmithKline299 participantsStarted Nov 2006

Beverly Hills, California, United States • Burbank, California, United States • Temecula, California, United States +30 more locations

Novel Approach to Stimulant Induced Weight Suppression and Its Impact on Growth

Treatment Of Patients With Social Anxiety Disorder

Find Trials by Condition in Miami

Ranibizumab for the Inhibition of Neovascularization in the Cornea Following Corneal Transplant Surgery

Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA)

Chronic Dosing Cross-Over Study to Assess the Efficacy and Safety of Glycopyrronium (PT001) in Adult Subjects With Intermittent Asthma or Mild to Moderate Persistent Asthma

Impact of a Human Papilloma Virus (HPV) Vaccine in HIV-Infected Young Women

Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients

To Study Generic Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Glenmark Generics, Ltd) in the Treatment of Acne Vulgaris.

The Use of Antibiotic Sinonasal Rinse After Sinus Surgery

Neuropsychological Norms for Ethnically Diverse Florida Elders

S0800, Nab-Paclitaxel, Doxorubicin, Cyclophosphamide, and Pegfilgrastim With or Without Bevacizumab in Treating Women With Inflammatory or Locally Advanced Breast Cancer

Extended Follow-Up Study for Subjects Who Participated in 2010 Study

Impact of SBI, a Medical Food, on Nutritional Status in Patients With HIV-associated Enteropathy

ARI103094-Follow-Up Study for REDUCE Study Subjects

Study Investigating the Impact Burden of Nocturia Using the Nocturia Impact Diary

Efficacy And Safety Of Tofacitinib In Psoriatic Arthritis: Comparator Study

Study of Adult T-Cell Leukemia/Lymphoma Among Carriers of HTLV-1

Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma

Early Life Factors and Respiratory Health in Mexico City Children

Large Diameter Advanta™ V12 Covered Stent Trial for Coarctation of the Aorta