Clinical Trials in Massachusetts

Showing 1621-1640 of 15,316 trials

ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer

NCT03587740

This research study is studying an investigational drug as a possible treatment for breast cancer that is positive for the protein Human Epidermal Growth Factor Receptor 2, also known as HER2-positive breast cancer. The drug involved in this study is: -ado-trastuzumab emtansine (T-DM1)

Breast Cancer

Dana-Farber Cancer Institute82 participantsStarted Aug 2018

Duarte, California, United States • Stamford, Connecticut, United States • Boston, Massachusetts, United States +11 more locations

RECRUITINGPhase 314 miles

52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism

NCT06689085

This is a 52-week open label single arm study + 24-Month long-term safety extension to investigate the effects of XYOSTED, as testosterone replacement therapy, on adolescent males with either primary or secondary hypogonadism. The study aims to determine the effectiveness of XYOSTED measured by continuation or induction of puberty in addition to XYOSTED dosage, safety and testosterone levels.

Hypogonadism, Male

Halozyme Therapeutics100 participantsStarted Mar 2025

Los Angeles, California, United States • San Diego, California, United States • San Francisco, California, United States +17 more locations

ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer

52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism

Find Trials by Condition in Massachusetts

Promoting Recovery After Brain Injury Using Focused Ultrasound

J-Valve Transfemoral Pivotal Study

Longitudinal Early-onset Alzheimer's Disease Study Protocol

Atezolizumab+Bevacizumab+SBRT in Unresectable HCC

Study of the Prevalence of Endogenous Hypercortisolism in Patients With Resistant Hypertension (MOMENTUM)

REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease

Study to Assess the Efficacy, Safety, and Tolerability of NOC-110 in Adults With Refractory or Unexplained Chronic Cough

BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)

A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation

Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)

An Open-label Extension Trial to Evaluate the Long-term Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children With Generalized Myasthenia Gravis

AQT90 FLEX NTproBNP2 Test Kit Matrix Comparison and Sample Stability Verification Study

Alloplastic Total Temporomandibular Joint (TMJ) Replacement Registry