Clinical Trials in Massachusetts

Showing 14221-14240 of 17,520 trials

A Study of Administration of Peginterferon Alfa-2a [Pegasys] by Autoinjector Versus Pre-filled Syringe in Patients With Chronic Hepatitis C

NCT01087944

This randomized, cross-over, open label study will compare the tolerability and handling of application of peginterferon alfa-2a \[Pegasys\] by autoinjector versus pre-filled syringe in patients with chronic hepatitis C, either on treatment with peginterferon alfa-2a for at least 12 weeks or treatment-naïve for peginterferon alfa-2a. Patients will be randomized to self-injection of 180mcg peginterferon alfa-2a once a week using either an autoinjector or a prefilled syringe for 3 weeks, then switch to use the other method of injection for another 3 weeks. Anticipated time on study treatment is 6 weeks. Target sample size is \<100 patients.

Hepatitis C, Chronic

Hoffmann-La Roche60 participantsStarted Mar 2010

Los Angeles, California, United States • Bradenton, Florida, United States • Orlando, Florida, United States +9 more locations

COMPLETEDPhase 314 miles

Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Cancer of the Uterus

NCT00002546

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether radiation therapy is more effective than combination chemotherapy in treating patients with cancer of the uterus. PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared to combination chemotherapy in treating patients with cancer of the uterus.

Sarcoma

Gynecologic Oncology Group216 participantsStarted Dec 1993

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Los Gatos, California, United States +62 more locations

A Study of Administration of Peginterferon Alfa-2a [Pegasys] by Autoinjector Versus Pre-filled Syringe in Patients With Chronic Hepatitis C

Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Cancer of the Uterus

Find Trials by Condition in Massachusetts

Effect of Psychological Intervention on Drop-out Rates in IVF

Imatinib (QTI571) in Pulmonary Arterial Hypertension

Proton Radiation Therapy With Cisplatin and Etoposide Followed by Surgery in Stage III Non-Small Cell Lung Cancer

Proton Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer

Does Weight Loss Surgery and Probiotic Supplementation Lead to a "Lean" Gut Microbiota?

Tai Chi and Aerobic Exercise for Fibromyalgia (FMEx)

Org 24448 (Ampakine) for Cognitive Deficits in Schizophrenia

Immunosuppressive Medications for Participants in ITN005CT (NCT00014911)

A Novel Diet-Phenotype Interaction Affecting Body Weight

Safety and Tolerability Trial of Inhaled Alpha1-Proteinase Inhibitor (Human), Hydrophobic Chromatography Process (Alpha-1 HC) in Subjects With Cystic Fibrosis

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Minocycline for the Treatment of Decreased Mental Function in HIV-Infected Adults

Antibody Persistence and Booster Dose Response in Subjects Who Received Menactra® Three Years Earlier in Study MTA26

A Phase 2 Dose-finding Study of Atacicept in Subjects With Rheumatoid Arthritis (AUGUST I)

Atacicept in Subjects With Optic Neuritis

First-Line Treatment for Locally Advanced or Metastatic Mesenchymal Epithelial Transition Factor (MET) - Positive Gastric, Lower Esophageal, or Gastroesophageal Junction (GEJ) Adenocarcinoma

Phase 3 Study of BI 207127 in Combination With Faldaprevir and Ribavirin for Treatment of Patients With Hepatitis C Infection, Including Patients Who Are Not Eligible to Receive Peginterferon: HCVerso2

Re-Evaluating the Inhibition of Stress Erosions: Gastrointestinal Bleeding Prophylaxis In ICU