Clinical Trials in Massachusetts

Showing 12981-13000 of 15,316 trials

Altered Brain GABA and Glutamate in Restless Legs Syndrome

NCT01109537

The purpose of the study is to understand the brain chemistry of people with Restless Legs Syndrome (RLS). The primary hypothesis is that patients with RLS will have reduced GABA levels in their Thalamus and elevated Glutamate levels in their Anterior Cingulate Cortex. The study will use MRS imaging to examine the regional levels of these neurochemicals, GABA and Glutamate, in the brain.

Restless Legs Syndrome

Brigham and Women's Hospital75 participantsStarted Apr 2010

Brighton, Massachusetts, United States

COMPLETED26 miles

Identification of a Plasma Proteomic Signature for Lung Cancer

NCT01752101

The primary objective is to identify a panel of plasma and/or serum proteins that differentiates the absence or presence of lung malignancy in samples obtained from subjects enrolled in this IRB/EC approved study with pulmonary nodules.

Precancerous ConditionsCarcinoma

Integrated Diagnostics475 participantsStarted Oct 2012

San Francisco, California, United States • Miami, Florida, United States • Anniston, Georgia, United States +9 more locations

COMPLETEDPhase 226 miles

Study to Evaluate the Efficacy and Safety of Dronabinol Metered Dose Inhaler (MDI) in Acute Treatment of Migraine Headache

NCT00123201

The primary objective of this study is to evaluate the efficacy and safety of dronabinol MDI for the acute treatment of moderate to severe migraine headache.

Migraine With AuraMigraine Without Aura

Solvay PharmaceuticalsStarted Sep 2005

Huntsville, Alabama, United States • Huntsville, Alabama, United States • Tucson, Arizona, United States +26 more locations

Altered Brain GABA and Glutamate in Restless Legs Syndrome

Identification of a Plasma Proteomic Signature for Lung Cancer

Study to Evaluate the Efficacy and Safety of Dronabinol Metered Dose Inhaler (MDI) in Acute Treatment of Migraine Headache

Find Trials by Condition in Massachusetts

Study to Evaluate the Effect of KB001-A on Time-to-Need for Antibiotic Treatment

Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP)

Cetuximab in Treating Patients With Persistent or Recurrent Cervical Cancer

Therapeutic Schools: Affect Management and HIV Prevention

Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function

A Phase II Study Comparing Low- and High-Dose Alemtuzumab and High-Dose Rebif® in Patients With Early, Active Relapsing-Remitting Multiple Sclerosis

Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Complicated Skin Infections

Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Subjects

Early Access to Cabazitaxel in Patients With Metastatic Hormone Refractory Prostate Cancer Previously Treated With a Docetaxel-containing Regimen

Efficacy Study of a ZT-1 Implant in Patients Suffering From Alzheimer's Disease

Epoprostenol for Injection (EFI/ACT-385781A) - Pulmonary Arterial Hypertension

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

Systemic and Local Diffusion of Ethanol After Administration of Ethanol 96% Formulated in a Gel and Ethanol 98% Solution by the Percutaneous Route, in Patients With Congenital Venous Malformations:Pharmacokinetic, Pharmacodynamic and Clinical Study.

A Study Evaluating the Effects of Siltuximab on the Heart in Patients With Monoclonal Gammopathy of Undetermined Significance, Smoldering Multiple Myeloma, or Indolent Multiple Myeloma

Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Male Subjects

Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects

Effect of Xenon and Therapeutic Hypothermia, on the Brain and on Neurological Outcome Following Brain Ischemia in Cardiac Arrest Patients