Study to Evaluate the Effect of KB001-A on Time-to-Need for Antibiotic Treatment

Exclusion Criteria

• •Treatment with antibiotics for acute illness within the 4 weeks before the Day 0 Visit
• •Use of systemic corticosteroids within the 4 weeks before the Day 0 Visit
• •Any change in regimen of CF maintenance therapies within the 4 weeks before the Day 0 Visit
• •History of sputum cultures positive for B. cepacia complex in the 2 years before the Screening Visit
• •History of organ transplantation
• •Current smoker (tobacco, marijuana, or any other material). Use of smokeless inhalers/vaporizers for these materials is also prohibited
• •History of drug addiction or alcohol abuse in the 12 months before the Screening Visit
• •History of hepatic disease (clinical cirrhosis or portal hypertension), renal dysfunction
• •Breast-feeding or pregnancy as evidenced by a positive blood pregnancy test
• •Receiving any investigational drug in the 16 weeks (or 5 half lives) before the Day 0 Visit, whichever is longer