Clinical Trials in Massachusetts

Showing 12641-12660 of 15,316 trials

Investigation of a Behavioral Substitute for Sunbathing

NCT00403377

RATIONALE: Understanding why sunbathers use or don't use sunless tanning products may help doctors plan effective ways to prevent skin cancer caused by sunbathing. PURPOSE: This phase I/II trial is studying attitudes about the use of sunless tanning products and how well sunless tanning products work as a substitute for sunbathing in healthy participants.

Melanoma (Skin)Skin Cancer

University of Massachusetts, Worcester307 participantsStarted Apr 2006

Worcester, Massachusetts, United States

TERMINATEDPhase 214 miles

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Homozygous for the F508del-CFTR Mutation

NCT00953706

The purpose of this study was to evaluate the safety and efficacy of ivacaftor in participants with cystic fibrosis (CF) who were aged 12 years or older and were homozygous for the F508del-CF transmembrane conductance regulator (CFTR) mutation. Ivacaftor is a potent and selective CFTR potentiator of wild-type, G551D, F508del, and R117H forms of human CFTR protein. Potentiators are pharmacological agents that increase the chloride ion transport properties of the channel in the presence of cyclic adenosine monophosphate (AMP)-dependent protein kinase A (PKA) activation.

Cystic Fibrosis

Vertex Pharmaceuticals Incorporated140 participantsStarted Sep 2009

Birmingham, Alabama, United States • Anchorage, Alaska, United States • Oakland, California, United States +31 more locations

Investigation of a Behavioral Substitute for Sunbathing

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Homozygous for the F508del-CFTR Mutation

Find Trials by Condition in Massachusetts

S0106 Cytarabine and Daunorubicin w/ or w/o Gemtuzumab Followed By HD Cytarabine and Either Gemtuzumab or Nothing in de Novo AML

A Phase 1 Study of IMGN289 in Adult Patients With EGFR-positive Solid Tumors

Transcutaneous Immunization With an Attenuated Listeria Monocytogenes Vector Vaccine

Study of Liberty Program on Women's Health and Intimate Partner Violence

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension

Effect of Daily Low Dose Aspirin on Exhaled Inflammatory Mediators in Normal Subjects

Cognitive-behavior Therapy for MS-Related Chronic Pain

24hr Imaging Of HCC After EOVIST

ch14.18 Pharmacokinetic Study in High-risk Neuroblastoma

Effectiveness of a Well-being Web-based Intervention

Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH Delivered From a Iontophoretic Patch Compared to Oral Treatment With Clomiphene or Placebo in Infertile Females

BG00010 (Neublastin) Phase 2 Multiple Dose Adaptive Design in Participants With Painful Lumbar Radiculopathy

Weight Watchers Online

Gut Microbiota Changes After Fecal Microbiota Transplantation

A Prospective, Open Label Study Evaluating Two Management Strategies on Gastrointestinal Symptoms in Patients Newly on Treatment With Pradaxa for the Prevention of Stroke and Systemic Embolism With Non-valvular Atrial Fibrillation

Remote Ischemic Preconditioning in Cardiac Surgery Trial

A Study of Combination Thalidomide Plus Dexamethasone Therapy vs. Dexamethasone Therapy Alone in Previously Untreated Subjects With Multiple Myeloma

Hormone Receptor Positive Metastatic Breast Cancer (HR+ mBC) BIIB021 Plus Aromasin Schedule Finding